Filters
Clonality
Type
Reactivity
Gene Name
Isotype
Host
Application
Clone
313 results for " EGFR Inhibitor" - showing 1-50
AZD9291, Inhibitor (Cat# AAA576635)
Full Name
AZD9291
Purity
98.0%
Pricing
$180/2 mg | $200/5 mg | $205/10 mg | $215/25 mg | $230/50 mg | $240/100 mg | $265/500 mg | $290/1 g | $255/200 mg | $200/1 mL (in DMSO) | $1,045/5x1 g
Chemical Structure
Foretinib (GSK1363089, XL880), Inhibitor (Cat# AAA384812)
Full Name
Foretinib (GSK1363089, XL880)
Purity
>98%
Pricing
$125/5 mg | $200/25 mg | $300/50 mg | $465/100 mg | $150/1 mL (in DMSO) | $2,050/5x100 mg
Immunohistochemistry (IHC)
(At 1/100 staining Human colorectal cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4 degree C overnight. An HRP conjugated anti-Mouse antibody was used as the secondary antibody.)
p38 MAPK, Monoclonal Antibody (Cat# AAA9629034)
Full Name
p38 MAPK Monoclonal Antibody
Gene Names
MAPK14; RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity-chromatography.
Pricing
$280/0.1 mL | $325/0.2 mL | $1,305/5x0.2 mL
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
c ABL (ABL1), Polyclonal Antibody (Cat# AAA9213319)
Full Name
c ABL (ABL1) Antibody (C-term)
Gene Names
ABL1; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl
Reactivity
Human
Applications
EIA, IHC-P, WB
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Erlotinib HCl, Inhibitor (Cat# AAA515069)
Full Name
Erlotinib HCl
Pricing
$195/5 mg | $445/25 mg | $1,780/5x25 mg
SU5402, Inhibitor (Cat# AAA579513)
Full Name
SU5402
Purity
98.0%
Pricing
$210/5 mg | $230/10 mg | $280/25 mg | $660/100 mg | $215/1 mL (in DMSO) | $2,695/5x100 mg
Structure
Palbociclib, Inhibitor (Cat# AAA577445)
Full Name
Palbociclib
Purity
99.2%
Pricing
$200/5 mg | $210/10 mg | $235/50 mg | $255/100 mg | $275/200 mg | $975/5x200 mg
Structure
Baricitinib, Inhibitor (Cat# AAA576687)
Full Name
Baricitinib (LY3009104, INCB028050)
Purity
98.9%
Pricing
$185/2 mg | $195/5 mg | $205/10 mg | $230/25 mg | $245/50 mg | $270/100 mg | $195/1 mL (in DMSO) | $950/5x100 mg
Testing Data
(Structure of MBS6030386N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride; NSC 718781; CP-358774, OSI-774, Ro 50-8231)
Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor, Biochemical (Cat# AAA6030386)
Full Name
Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231)
Purity
Highly Purified
100%
100%
Pricing
$385/100 mg | $600/250 mg | $850/500 mg | $1,095/1 g | $4,925/5x1 g
Western Blot (WB)
(MBS632984 specifically binds to tyrosine phosphorylated EGF receptors but not other phosphorylated tyrosine kinases. Western blot analysis of extracts from cells expressing different activated tyrosine kinase proteins, using MBS632984 (upper) or T9228-75B (lower).)
Epidermal Growth Factor Receptor, Monoclonal Antibody (Cat# AAA632984)
Full Name
Epidermal Growth Factor Receptor, phosphorylated (Tyr1173) (erbB, EGFR)
Gene Names
EGFR; ERBB; HER1; mENA; ERBB1; PIG61
Reactivity
Human
Applications
WB, IP, IHC, ICC
Purity
Supernatant
Supernatant
Supernatant
Pricing
$650/0.1 mL | $2,905/5x0.1 mL
Protein Kinase Inhibitor PP2, Inhibitor (Cat# AAA655465)
Full Name
Protein Kinase Inhibitor PP2 (PKI PP2, 4-amino-5-(4-chlorophenyl)-7- (t-butyl)pyrazolo[3,4-d]pyrimidine)
Purity
Highly Purified
~98% (TLC)
~98% (TLC)
Pricing
$435/1 mg | $1,950/5x1 mg
Molecular Structure
CHIR-99021, Inhibitor (Cat# AAA515063)
Full Name
CHIR-99021
Purity
>98% (TLC); NMR (Conforms)
Pricing
$175/1 mg | $275/5 mg | $1,015/5x5 mg
Ginsenoside Rg3, Inhibitor (Cat# AAA578434)
Full Name
Ginsenoside Rg3
Purity
98.1%
Pricing
$185/5 mg | $195/10 mg | $225/25 mg | $240/50 mg | $305/100 mg | $430/200 mg | $1,660/5x200 mg
Structure
PP2, Inhibitor (Cat# AAA578828)
Full Name
PP2
Purity
95.7%
Pricing
$195/2 mg | $210/5 mg | $250/10 mg | $315/25 mg | $395/50 mg | $615/100 mg | $210/1 mL (in DMSO) | $2,500/5x100 mg
Structure
AST-1306, Inhibitor (Cat# AAA578882)
Full Name
AST-1306
Purity
99.5%
Pricing
$250/2 mg | $295/5 mg | $360/10 mg | $510/25 mg | $885/50 mg | $360/1 mL (in DMSO) | $3,715/5x50 mg
Molecular Structure
Fasudil HCl, Inhibitor (Cat# AAA515075)
Full Name
Fasudil HCl
Purity
>98% (TLC); NMR (Conforms)
Pricing
$210/10 mg | $445/50 mg | $1,780/5x50 mg
Structure
MTX-211, Inhibitor (Cat# AAA5750105)
Full Name
MTX-211
Purity
99.5%
Pricing
$240/1 mg | $305/2 mg | $445/5 mg | $610/10 mg | $1,080/25 mg | $1,595/50 mg | $2,250/100 mg | $445/1 mL (in DMSO) | $9,855/5x100 mg
Chemical Structure
(Chemical structure of Gefitinib (SIH-445), a EGFR-Kinase inhibitor. CAS #: 184475-35-2. Molecular Formula: C22H24ClFN4O3. Molecular Weight: 446.9 g/mol.)
Gefitinib, Small Molecule (Cat# AAA808145)
Full Name
Gefitinib
Purity
>99%
Pricing
$190/50 mg | $335/250 mg | $640/5x50 mg | $1,280/5x250 mg
Testing Data
(PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 uM for p110alpha, p110beta, p110delta, p110gamma, DNA-PK, mTOR and PDGFR, respectively. PP121 also inhibits Abl, Hck, Src,Src(T338I), VEGFR2, EGFR EphB4 with IC50 of 0.018, 0.008, 0.014, 0.22, 0.012, 0.26, 0.19 uM, respectively. PP121 exhibits no significant effect on receptor serine/threonine kinases (RSTKs). PP121 blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor. PP121 achieves its dual potency by targeting a residue (Glu310 in Src) that has been structurally conserved between kinase families. PP121 potently and dose-dependently blocked the phosphorylation of Akt, p70S6K and S6 in these cells. [1])
Structure
PHA-665752, Inhibitor (Cat# AAA578696)
Full Name
PHA-665752
Purity
99.4%
Pricing
$205/5 mg | $230/10 mg | $315/25 mg | $455/50 mg | $705/100 mg | $975/200 mg | $230/1 mL (in DMSO) | $4,125/5x200 mg
Structure
WZ3146, Inhibitor (Cat# AAA579266)
Full Name
WZ3146
Purity
98.95%
Pricing
$210/2 mg | $250/5 mg | $335/10 mg | $470/25 mg | $745/50 mg | $360/1 mL (in DMSO) | $3,080/5x50 mg
Testing Data
(Gefitinib (Iressa) is a novel potent EGFR tyrosine kinase and Akt phosphorylations inhibitor with IC50 of 37, 26 and 57 nM for Tyr1173, Tyr1173 and Tyr992 in, respectively, the low and high EGFR expressing cell lines. Immunoblot analysis of whole cell lysates revealed that in general gefitinib effectively inhibited all tyrosine phosphorylation sites on EGFR in both the high and low-EGFR-expressing cell lines. However, the phosphorylation sites Tyr1173 and Tyr992 were less sensitive requiring higher concentrations of gefitinib for inhibition. As was the case for ERK, gefitinib fails to effectively inhibit AKT phosphorylation in the high-EGFR- expressing cell line indicating that EGFR is not the major activator of AKT in this cell line. The low IC50 (7 nM), however show that the weak induction of AKT phosphorylation by EGFR in this cell line is efficiently blocked by gefitinib. Gefitinib inhibits AKT phosphorylations, with IC50 values of 220 and 263 nM, in the low-EGFR- and -EGFRvIII-expressing cell lines, respectively. [1] MCF10A cells are nontransformed breast epithelial cells that require EGF to proliferate.)
Gefitinib, Inhibitor (Cat# AAA8506564)
Full Name
Gefitinib (Iressa)
Purity
>99%
Pricing
$295/1 g | $1,255/5x1 g
Structure
WZ4002, Inhibitor (Cat# AAA578801)
Full Name
WZ4002
Purity
98.1%
Pricing
$200/5 mg | $225/10 mg | $265/25 mg | $330/50 mg | $480/100 mg | $765/200 mg | $200/1 mL (in DMSO) | $3,165/5x200 mg
AZD-9291, Inhibitor (Cat# AAA578501)
Full Name
AZD-9291 mesylate
Purity
99.38%
Pricing
$205/5 mg | $210/10 mg | $215/25 mg | $230/50 mg | $240/100 mg | $270/500 mg | $290/1 g | $255/200 mg | $215/1 mL (in DMSO) | $1,045/5x1 g
Structure
WZ8040, Inhibitor (Cat# AAA579267)
Full Name
WZ8040
Purity
98.0%
Pricing
$210/2 mg | $275/5 mg | $380/10 mg | $620/25 mg | $950/50 mg | $275/1 mL (in DMSO) | $4,010/5x50 mg
Structure
PP1, Inhibitor (Cat# AAA578760)
Full Name
PP1
Purity
100.0%
Pricing
$200/2 mg | $230/5 mg | $260/10 mg | $340/25 mg | $405/50 mg | $575/100 mg | $230/1 mL (in DMSO) | $2,330/5x100 mg
Chemical Structure
(Chemical structure of AG 1478 (SIH-425), a EGFR kinase inhibitor. CAS #: 175178-82-2. Molecular Formula: C16H14ClN3O2. Molecular Weight: 315.8 g/mol.)
AG 1478, Small Molecule (Cat# AAA808127)
Full Name
AG 1478
Purity
>=98% (HPLC)
Pricing
$210/5 mg | $430/25 mg | $1,695/5x25 mg | $720/5x5 mg
Structure
Mubritinib, Inhibitor (Cat# AAA578692)
Full Name
Mubritinib (TAK 165)
Purity
99.57%
Pricing
$205/10 mg | $240/25 mg | $300/50 mg | $430/100 mg | $690/200 mg | $195/1 mL (in DMSO) | $2,845/5x200 mg
FIIN-3, Inhibitor (Cat# AAA579596)
Full Name
FIIN-3
Purity
97.6%
Pricing
$230/1 mg | $265/2 mg | $350/5 mg | $480/10 mg | $830/25 mg | $1,245/50 mg | $1,855/100 mg | $475/1 mL (in DMSO) | $8,070/5x100 mg
Chemical Structure
Lazertinib, Inhibitor (Cat# AAA5750588)
Full Name
Lazertinib
Purity
98.00%
Pricing
$200/1 mg | $210/2 mg | $235/5 mg | $290/10 mg | $390/25 mg | $460/50 mg | $745/100 mg | $250/1 mL (in DMSO) | $3,085/5x100 mg
Structure
BIX 02188, Inhibitor (Cat# AAA578876)
Full Name
BIX 02188
Purity
99.0%
Pricing
$210/2 mg | $265/5 mg | $360/10 mg | $475/25 mg | $340/1 mL (in DMSO) | $1,880/5x25 mg
Mutant EGFR inhibitor, Inhibitor (Cat# AAA577442)
Full Name
Mutant EGFR inhibitor
Purity
97.7%
Pricing
$245/1 mg | $325/2 mg | $405/5 mg | $555/10 mg | $900/25 mg | $1,525/50 mg | $2,090/100 mg | $555/1 mL (in DMSO) | $9,130/5x100 mg
Structure
Butein, Inhibitor (Cat# AAA578970)
Full Name
Butein
Purity
99.11%
Pricing
$200/2 mg | $225/5 mg | $245/10 mg | $350/25 mg | $520/50 mg | $865/100 mg | $225/1 mL (in DMSO) | $3,615/5x100 mg
Structure
Canertinib, Inhibitor (Cat# AAA578704)
Full Name
Canertinib (CI-1033)
Purity
99.0%
Pricing
$185/5 mg | $205/10 mg | $210/25 mg | $230/50 mg | $250/100 mg | $335/200 mg | $205/1 mL (in DMSO) | $1,240/5x200 mg
Structure
lavendustin A, Inhibitor (Cat# AAA5750046)
Full Name
lavendustin A
Purity
98.2%
Pricing
$205/1 mg | $240/2 mg | $295/5 mg | $370/10 mg | $630/25 mg | $295/1mL*10mM (in DMSO) | $2,550/5x25 mg
Structure
AZD-9291 mesylate, Inhibitor (Cat# AAA3601763)
Full Name
AZD-9291 mesylate
Purity
>98% (HPLC)
Pricing
$185/5 mg | $200/10 mg | $205/25 mg | $225/100 mg | $240/200 mg | $795/5x200 mg
Avitinib, Inhibitor (Cat# AAA578129)
Full Name
Avitinib
Purity
99.9%
Pricing
$205/2 mg | $225/5 mg | $260/10 mg | $370/25 mg | $490/50 mg | $705/100 mg | $225/1 mL (in DMSO) | $2,905/5x100 mg
Structure
CNX-2006, Inhibitor (Cat# AAA578585)
Full Name
CNX-2006
Purity
99.2%
Pricing
$205/2 mg | $225/5 mg | $270/10 mg | $355/25 mg | $540/50 mg | $870/100 mg | $240/1 mL (in DMSO) | $3,655/5x100 mg
Structure
CUDC-101, Inhibitor (Cat# AAA578166)
Full Name
CUDC-101
Purity
96.3%
Pricing
$175/2 mg | $195/5 mg | $225/10 mg | $265/25 mg | $330/50 mg | $480/100 mg | $200/1 mL (in DMSO) | $1,900/5x100 mg
AZD3759, Inhibitor (Cat# AAA5750100)
Full Name
AZD3759 hydrochloride
Purity
99.4%
Pricing
$195/2 mg | $215/5 mg | $240/10 mg | $300/25 mg | $405/50 mg | $600/100 mg | $980/200 mg | $225/1 mL (in DMSO) | $4,140/5x200 mg
AZD3759, Inhibitor (Cat# AAA578526)
Full Name
AZD3759
Purity
99.4%
Pricing
$190/5 mg | $205/10 mg | $210/25 mg | $240/50 mg | $290/100 mg | $1,045/5x100 mg
Structure
Icotinib, Inhibitor (Cat# AAA578718)
Full Name
Icotinib
Purity
98.8%
Pricing
$200/2 mg | $210/5 mg | $235/10 mg | $300/25 mg | $210/1mL*10mM (in DMSO) | $1,050/5x25 mg
EBE-A22, Inhibitor (Cat# AAA579675)
Full Name
EBE-A22
Purity
99.7%
Pricing
$230/1 mg | $260/2 mg | $315/5 mg | $400/10 mg | $650/25 mg | $775/50 mg | $1,140/100 mg | $290/1 mL (in DMSO) | $4,860/5x100 mg
Chemical Structure
(Chemical structure of BIBW 2992 (SIH-496), a EGFR and HER2 kinase inhibitor. CAS #: 439081-18-2. Molecular Formula: C24H25ClFN5O3. Molecular Weight: 485.9 g/mol.)
BIBW 2992, Small Molecule (Cat# AAA808195)
Full Name
BIBW 2992
Purity
>99%
Pricing
$280/5 mg | $655/25 mg | $2,725/5x25 mg | $1,015/5x5 mg
CP-724714, Inhibitor (Cat# AAA579919)
Full Name
CP-724714
Purity
98.82%
Pricing
$205/2 mg | $235/5 mg | $295/10 mg | $430/25 mg | $595/50 mg | $835/100 mg | $235/1 mL (in DMSO) | $3,495/5x100 mg
AG 494, Inhibitor (Cat# AAA5750067)
Full Name
AG 494
Purity
99.5%
Pricing
$185/2 mg | $210/5 mg | $230/10 mg | $285/25 mg | $355/50 mg | $480/100 mg | $570/200 mg | $2,295/5x200 mg
RG 14620, Inhibitor (Cat# AAA579671)
Full Name
RG 14620
Purity
99.6%
Pricing
$200/5 mg | $225/10 mg | $310/25 mg | $395/50 mg | $570/100 mg | $925/200 mg | $205/1 mL (in DMSO) | $3,885/5x200 mg
EGF816, Inhibitor (Cat# AAA579636)
Full Name
EGF816
Purity
98.6%
Pricing
$200/1 mg | $210/2 mg | $235/5 mg | $290/10 mg | $400/25 mg | $640/50 mg | $1,110/100 mg | $240/1 mL (in DMSO) | $4,720/5x100 mg
Structure
JCN037, Inhibitor (Cat# AAA5759229)
Full Name
JCN037
Purity
98.00%
Pricing
$200/1 mg | $285/5 mg | $355/10 mg | $495/25 mg | $715/50 mg | $1,110/100 mg | $295/1 mL (in DMSO) | $4,720/5x100 mg
Chemical Structure
(Chemical structure of AG 494 (SIH-491), a EGF receptor tyrosine kinase inhibitor. CAS #: 133550-35-3. Molecular Formula: C16H12N2O3. Molecular Weight: 280.3 g/mol.)
AG 494, Small Molecule (Cat# AAA808190)
Full Name
AG 494
Purity
>=98% (TLC)
Pricing
$205/10 mg | $435/50 mg | $700/5x10 mg | $1,720/5x50 mg
