p70 S6K Recombinant Protein | S6k recombinant protein
p70 S6K protein
Purity
p70 S6K protein was purified using a a proprietary chromatographic technique.
Synonyms
p70 S6K; p70 S6K protein; p S6K 70; Ribosomal protein S6 kinase beta-1 protein; p S6K-70; p S6K-70 protein; P70 protein; p S6K 70 protein; S6k recombinant protein
Host
Human
Purity/Purification
p70 S6K protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in a storage buffer consisting of 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF and 25% glycerol
Sequence Length
297
Protein Type
Recombinant
Biological Significance
Activation of cell growth leads to the multiple phosphorylation of 40S ribosomal protein S6. The kinase responsible for controlling this event is termed p70S6K. Northern blot analysis shows p70S6K to be ubiquitously expressed in human adult tissues. p70S6K is activated by serum stimulation, and the serum- induced activation is inhibited by wortmannin and rapamycin. p70S6k activity undergoes changes in the cell cycle and increases 20-fold in G1 cells released from G0. The kinase is reactivated 10-fold when cells released from a nocodazole- induced metaphase block enter G1 of the next cell cycle. The immunosuppressive agent rapamycin induces inactivation of p70s6k with no effect on other mitogen-activated kinases.
Expression System
Sf-9 insect cells
Preparation and Storage
Store at -80 degree C
Related Product Information for S6k recombinant protein
Purified recombinant Human p70 S6K protein
Product Categories/Family for S6k recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
76 kDa
NCBI Official Full Name
p70 S6 kinase, partial
UniProt Protein Name
p70 S6 kinase
UniProt Gene Name
S6k
UniProt Entry Name
L0L0Y5_CARMA
Similar Products
Product Notes
The p70 S6K s6k (Catalog #AAA5304629) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "p70 S6K, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
