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S100A16 recombinant protein

Recombinant Human S100A16 protein

Gene Names
S100A16; AAG13; S100F; DT1P1A7
Purity
>90% as determined by SDS-PAGE
Synonyms
S100A16; Recombinant Human S100A16 protein; AAG13 Protein; Human; DT1P1A7 Protein; MGC17528 Protein; S100F Protein; S100A16 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.
Species
Homo sapiens (Human)
Protein Construction
A DNA sequence encoding the human S100A16 (Ser2-Ser103) was fused with His tag
Reconstitution
Reconstitute in sterile water for a stock solution.
Preparation and Storage
Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Related Product Information for S100A16 recombinant protein
S1A16 is a member of S1 protein super family that carries calcium-binding EF-hand motifs. S1 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S1A16 expression was found to be astrocyte-specific. The S1A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S1A16 in the apo state has been obtained both in the solid state and in solution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S1A16 was also calculated in the calcium(II)-bound form. Differently from most S1 proteins, the conformational rearrangement upon calcium binding is minor. Immunoprecipitation analysis revealed that S1A16 could physically interact with tumor suppressor protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S1A16 led to the inhibition or activation of the expression of p53-responsive genes, respectively. S1A16 protein is a novel adipogenesis-promoting factor.
Product Categories/Family for S100A16 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,801 Da
NCBI Official Full Name
protein S100-A16
NCBI Official Synonym Full Names
S100 calcium binding protein A16
NCBI Official Symbol
S100A16
NCBI Official Synonym Symbols
AAG13; S100F; DT1P1A7
NCBI Protein Information
protein S100-A16; protein S100-F; aging-associated protein 13; S100 calcium-binding protein A16; aging-associated gene 13 protein
UniProt Protein Name
Protein S100-A16
Protein Family
UniProt Gene Name
S100A16
UniProt Synonym Gene Names
S100F
UniProt Entry Name
S10AG_HUMAN

Uniprot Description

S100A16: Calcium-binding protein. Binds one calcium ion per monomer. Belongs to the S-100 family.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; nucleolus; plasma membrane; cytosol

Molecular Function: protein homodimerization activity; calcium ion binding

Biological Process: response to calcium ion

Research Articles on S100A16

Similar Products

Product Notes

The S100A16 s100a16 (Catalog #AAA1562321) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "S100A16, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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