Rotavirus A Intermediate capsid protein VP6 Recombinant Protein | VP6 recombinant protein

Recombinant Rotavirus A Intermediate capsid protein VP6

Cat. Num. AAA9420891

• Reactivity: ROTRF
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: Rotavirus A Intermediate capsid protein VP6; Recombinant Rotavirus A Intermediate capsid protein VP6; VP6 recombinant protein

• Host: E Coli
• Reactivity: ROTRF
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Full Length, 1-397aa

• Tag Info: His-tag
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for VP6 recombinant protein

Intermediate capsid protein that self assbles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid rain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nacent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.

NCBI and Uniprot Product Information

• NCBI GI #: 8247962
• UniProt Accession #: P04509
• Molecular Weight: 48.9kD
• NCBI Official Full Name: Intermediate capsid protein VP6
• UniProt Protein Name: Intermediate capsid protein VP6

Uniprot Description

Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.