E3 ubiquitin-protein ligase RNF167 (RNF167) Recombinant Protein | RNF167 recombinant protein
Recombinant Human E3 ubiquitin-protein ligase RNF167 (RNF167)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 [PubMed 16314844]).[supplied by OMIM, Mar 2008]
Uniprot Description
RNF167: May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Protein type: Membrane protein, integral; EC 6.3.2.19; Ubiquitin ligase; Ligase; EC 6.3.2.-; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: cytoplasm; endomembrane system; integral to membrane
Molecular Function: ligase activity; protein binding; ubiquitin-protein ligase activity; zinc ion binding
Biological Process: negative regulation of cell cycle; protein polyubiquitination
Research Articles on RNF167
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Product Notes
The RNF167 rnf167 (Catalog #AAA7028751) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 25-350aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the RNF167 rnf167 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LIRATSDHNA SMDFADLPAL FGATLSQEGL QGFLVEAHPD NACSPIAPPP PAPVNGSVFI ALLRRFDCNF DLKVLNAQKA GYGAAVVHNV NSNELLNMVW NSEEIQQQIW IPSVFIGERS SEYLRALFVY EKGARVLLVP DNTFPLGYYL IPFTGIVGLL VLAMGAVMIA RCIQHRKRLQ RNRLTKEQLK QIPTHDYQKG DQYDVCAICL DEYEDGDKLR VLPCAHAYHS RCVDPWLTQT RKTCPICKQP VHRGPGDEDQ EEETQGQEEG DEGEPRDHPA SERTPLLGSS PTLPTSFGSL APAPLVFPGP STDPPLSPPS SPVILV. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase RNF167 (RNF167), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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