RING finger protein 114 (RNF114) Recombinant Protein | RNF114 recombinant protein

Recombinant Human RING finger protein 114 (RNF114)

Cat. Num. AAA1379443

• Gene Names: RNF114; ZNF313; PSORS12
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: RING finger protein 114 (RNF114); Recombinant Human RING finger protein 114 (RNF114); RING finger protein 114; Zinc finger protein 228; Zinc finger protein 313; RNF114 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-228aa; Full Length
• Sequence: MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ
• Sequence Length: 228

• Species: Homo sapiens (Human)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

SDS-PAGE

Related Product Information for RNF114 recombinant protein

E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.

Product Categories/Family for RNF114 recombinant protein

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 8923898
• NCBI GeneID: 55905
• NCBI Accession #: NP_061153.1
• NCBI GenBank Nucleotide #: NM_018683.3
• UniProt Accession #: Q9Y508; Q6N0B0; B2RDQ9; B4DWY5; E1P627
• Molecular Weight: 52.7 kDa
• NCBI Official Full Name: E3 ubiquitin-protein ligase RNF114
• NCBI Official Synonym Full Names: ring finger protein 114
• NCBI Official Symbol: RNF114
• NCBI Official Synonym Symbols: ZNF313; PSORS12
• NCBI Protein Information: E3 ubiquitin-protein ligase RNF114; zinc finger protein 228; zinc finger protein 313
• UniProt Protein Name: E3 ubiquitin-protein ligase RNF114
• Protein Family: E3 ubiquitin-protein ligase
• UniProt Gene Name: RNF114
• UniProt Synonym Gene Names: ZNF228; ZNF313
• UniProt Entry Name: RN114_HUMAN

Uniprot Description

ZNF313: May play a role in spermatogenesis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system; Transcription factor; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 20q13.13

Cellular Component: cytoplasm; intracellular; nucleus

Molecular Function: zinc ion binding; ligase activity

Biological Process: multicellular organismal development; protein ubiquitination; spermatogenesis; cell differentiation