Regulator of G-protein signaling 8 (RGS8) Recombinant Protein | RGS8 recombinant protein

Recombinant Human Regulator of G-protein signaling 8 (RGS8)

Cat. Num. AAA950437

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Regulator of G-protein signaling 8 (RGS8); Recombinant Human Regulator of G-protein signaling 8 (RGS8); RGS8 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-180, Full length protein
• Sequence: MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
• Sequence Length: 180

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RGS8 recombinant protein

This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.

NCBI and Uniprot Product Information

• NCBI GI #: 156416024
• NCBI GeneID: 85397
• NCBI Accession #: NP_001095920.1
• NCBI GenBank Nucleotide #: NM_001102450.2
• UniProt Accession #: P57771; Q3SYD2; B4DGL9
• Molecular Weight: 22,970 Da
• NCBI Official Full Name: regulator of G-protein signaling 8 isoform 2
• NCBI Official Synonym Full Names: regulator of G protein signaling 8
• NCBI Official Symbol: RGS8
• NCBI Protein Information: regulator of G-protein signaling 8
• UniProt Protein Name: Regulator of G-protein signaling 8
• Protein Family: Regulator of G-protein signaling
• UniProt Gene Name: RGS8
• UniProt Synonym Gene Names: RGS8

NCBI Description

This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]

Uniprot Description

Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:18434541). Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling ().