Rat regulator of G-protein signaling 7 ELISA Kit | RGS7 elisa kit

Rat Regulator of G-protein signaling 7-binding protein, RGS7 ELISA Kit

Cat. Num. AAA9334954

• Reactivity: Rat
• Synonyms: regulator of G-protein signaling 7; Rat Regulator of G-protein signaling 7-binding protein; RGS7 ELISA Kit; Rat Regulator of G-protein signaling 7-binding protein (RGS7) ELISA kit; OTTHUMP00000037994; regulator of G-protein signaling RGS7; regulator of G-protein signalling 7; RGS7 elisa kit

• Reactivity: Rat

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 9507047
• NCBI GeneID: 54296
• NCBI Accession #: NP_062216.1
• NCBI GenBank Nucleotide #: NM_019343.1
• UniProt Accession #: P49803; Q9R0R0
• Molecular Weight: 55,691 Da
• NCBI Official Full Name: regulator of G-protein signaling 7
• NCBI Official Synonym Full Names: regulator of G-protein signaling 7
• NCBI Official Symbol: Rgs7
• NCBI Protein Information: regulator of G-protein signaling 7
• UniProt Protein Name: Regulator of G-protein signaling 7
• Protein Family: Regulator of G-protein signaling
• UniProt Gene Name: Rgs7
• UniProt Synonym Gene Names: RGS7
• UniProt Entry Name: RGS7_RAT

NCBI Description

acts as a GTPase activating protein; regulates activation and deactivation kinetics of G-protein coupled inward rectifier K+ channel; binds Galphao; Galphai3, and Galphaz [RGD, Feb 2006]

Uniprot Description

RGS7: inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations. Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP. Four alternatively spliced isoforms have been described.

Protein type: GAPs; GAPs, RGS

Cellular Component: protein complex; cytoplasm; plasma membrane; heterotrimeric G-protein complex; cytosol; nucleus

Molecular Function: signal transducer activity; protein binding; G-protein beta-subunit binding; GTPase activator activity

Biological Process: G-protein coupled receptor protein signaling pathway; regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity