RNA Exonuclease 1 Recombinant Protein | REXO1 recombinant protein
Recombinant Human RNA Exonuclease 1
Gene Names
REXO1; REX1; ELOABP1; EloA-BP1; TCEB3BP1
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
RNA Exonuclease 1; Recombinant Human RNA Exonuclease 1; REXO1 Human; RNA Exonuclease 1 Human Recombinant; RNA exonuclease 1 homolog; Elongin-A-binding protein 1; EloA-BP1; Transcription elongation factor B polypeptide 3-binding protein 1; REXO1; ELOABP1; KIAA1138; TCEB3BP1; REXO1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The REXO1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSIYAL DCEMSYTTYG LELTRVTVVD TDVHVVYDTF VKPDNEIVDY NTRFSGVTEA DLADTSVTLR DVQAVLLSMF SADTILIGHS LESDLLALKV IHSTVVDTSV LFPHRLGLPY KRSLRNLMAD YLRQIIQDNV DGHSSSEDAG ACMHLVIWKV REDAKTKR
Sequence Length
1221
Related Product Information for REXO1 recombinant protein
Description: REXO1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 198 amino acids (1060-1221a.a) and having a molecular mass of 22.3kDa. REXO1 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: REXO1 is an exonuclease domain-containing protein which binds to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. REXO1 is a putative stem cell marker and is highly expressed in embryonic and adult stem cells.
Introduction: REXO1 is an exonuclease domain-containing protein which binds to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. REXO1 is a putative stem cell marker and is highly expressed in embryonic and adult stem cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
131,510 Da
NCBI Official Full Name
RNA exonuclease 1 homolog
NCBI Official Synonym Full Names
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
NCBI Official Symbol
REXO1
NCBI Official Synonym Symbols
REX1; ELOABP1; EloA-BP1; TCEB3BP1
NCBI Protein Information
RNA exonuclease 1 homolog; elongin A binding protein 1; elongin A-binding protein 1; elongin-A-binding protein 1; transcription elongation factor B polypeptide 3 binding protein 1; transcription elongation factor B polypeptide 3-binding protein 1
UniProt Protein Name
RNA exonuclease 1 homolog
Protein Family
UniProt Gene Name
REXO1
UniProt Synonym Gene Names
ELOABP1; KIAA1138; TCEB3BP1; EloA-BP1
UniProt Entry Name
REXO1_HUMAN
Uniprot Description
REXO1: Seems to have no detectable effect on transcription elongation in vitro. Belongs to the REXO1/REXO3 family.
Protein type: Hydrolase; EC 3.1.-.-
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleoplasm
Molecular Function: nucleic acid binding; exonuclease activity
Research Articles on REXO1
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Product Notes
The REXO1 rexo1 (Catalog #AAA146451) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MRGSHHH HHH GMASMTGGQQ MGRDLYDDDD KDRWGS IYAL DCEMSYTTYG LELTRVTVVD TDVHVVYDTF VKPDNEIVDY NTRFSGVTEA DLADTSVTLR DVQAVLLSMF SADTILIGHS LESDLLALKV IHSTVVDTSV LFPHRLGLPY KRSLRNLMAD YLRQIIQDNV DGHSSSEDAG ACMHLVIWKV REDAKTKR. It is sometimes possible for the material contained within the vial of "RNA Exonuclease 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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