SDS-Page
(SDS-PAGE: 2ug unactive JNK2a2.)
JNK2 alpha2, unactive Active Protein
JNK2 alpha2, unactive, Recombinant, Human (c-Jun N-terminal Kinase 2, JNK2, JNK2alpha, JNK2A, JNK-55, Mitogen-activated Protein Kinase 9, MAP Kinase 9, MAPK 9, MAPK9, PRKM9, p54a, p54aSAPK, Stress-activated Protein Kinase 1a, SAPK1a, SAPK, Stress-activate
Purity
Highly Purified90%. Purified using Ni-NTA agarose. Mr ~51kD (SDS-PAGE and Coomassie blue staining)
Synonyms
JNK2 alpha2; unactive; Recombinant; Human (c-Jun N-terminal Kinase 2; JNK2; JNK2alpha; JNK2A; JNK-55; Mitogen-activated Protein Kinase 9; MAP Kinase 9; MAPK 9; MAPK9; PRKM9; p54a; p54aSAPK; Stress-activated Protein Kinase 1a; SAPK1a; SAPK; Stress-activate; unactive active protein
Host
Recombinant human
Purity/Purification
Highly Purified
90%. Purified using Ni-NTA agarose. Mr ~51kD (SDS-PAGE and Coomassie blue staining)
90%. Purified using Ni-NTA agarose. Mr ~51kD (SDS-PAGE and Coomassie blue staining)
Form/Format
100ug enzyme in 50ul of 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1% 2-mercaptoethanol, 0.02% Brij-35, 50% glycerol.
Specific Activity
80u/mg when maximally activated. One unit of JNK2a2/SAPK1a activity is defined as 1nmol phosphate incorporated into GST-ATF2 per minute.
Preparation and Storage
Stable for 6 months at -20 degree C from date of shipment.
SDS-Page
(SDS-PAGE: 2ug unactive JNK2a2.)
SDS-Page
(SDS-PAGE: 2ug unactive JNK2a2.)
Related Product Information for JNK2 alpha2, unactive active protein
Jun Kinases (JNK), also called stress-activated protein (SAP) kinases, are proline-directed, serine/threonine-specific kinases that require phosphorylation on tyrosine for phosphotransferase activity. JNK was originally shown to phosphorylate microtubule-associated protein-2, but c-Jun and ATF2 appears to be an important physiological target of this kinase. Phosphorylation of Thr69 and Thr71 of ATF2 by JNK is important for the transcriptional activity of ATF2. cDNA cloning studies with rat and human libraries have shown that there are several isoforms of the JNK family. Many stimuli activate JNK including heat shock, hyperosmotic shock, UV irradiation, exposure to protein synthesis inhibitors such as cycloheximide and anisomycin, and treatment with proinflammatory cytokines such as tumor necrosis factor-a.
Recombinant full-length human JNK2a2/SAPK1a with an N-terminal His-tag, expressed in Sf21 cells. Accession number L31951
Recombinant full-length human JNK2a2/SAPK1a with an N-terminal His-tag, expressed in Sf21 cells. Accession number L31951
Product Categories/Family for JNK2 alpha2, unactive active protein
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Product Notes
The JNK2 alpha2, unactive (Catalog #AAA637693) is an Active Protein produced from Recombinant human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "JNK2 alpha2, unactive, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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