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Western Blot (Western Blot analysis using PROZ antibodyWestern Blot showing PROZ antibody used against human plasma (1).)

Mouse PROZ Monoclonal Antibody | anti-PROZ antibody

PROZ antibody

Applications
ELISA, Western Blot
Synonyms
PROZ; Monoclonal Antibody; PROZ antibody; Monoclonal PROZ; Anti-PROZ; Anti PROZ; Protein Z; anti-PROZ antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2B4
Form/Format
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
422
Applicable Applications for anti-PROZ antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:10,000
WB: 1:500-1:2000
Biological Significance
PROZ appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles.
Cross-Reactivity
Human
Immunogen
PROZ antibody was raised in Mouse using a purified recombinant fragment of PROZ expressed in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot

(Western Blot analysis using PROZ antibodyWestern Blot showing PROZ antibody used against human plasma (1).)

Western Blot (Western Blot analysis using PROZ antibodyWestern Blot showing PROZ antibody used against human plasma (1).)
Related Product Information for anti-PROZ antibody
Mouse monoclonal PROZ antibody
Product Categories/Family for anti-PROZ antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
47,053 Da
UniProt Protein Name
Vitamin K-dependent protein Z
UniProt Gene Name
PROZ
UniProt Entry Name
PROZ_HUMAN

Uniprot Description

PROZ: Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: endoplasmic reticulum lumen; Golgi lumen

Molecular Function: serine-type endopeptidase activity; calcium ion binding

Biological Process: cellular protein metabolic process; blood coagulation; post-translational protein modification; proteolysis; peptidyl-glutamic acid carboxylation

Disease: Protein Z Deficiency

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Product Notes

The PROZ proz (Catalog #AAA830890) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PROZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:10,000 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PROZ proz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PROZ, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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