RNA-binding protein with multiple splicing (RBPMS) Recombinant Protein | RBPMS recombinant protein

Recombinant Human RNA-binding protein with multiple splicing (RBPMS)

Cat. Num. AAA1344569

• Gene Names: RBPMS; HERMES
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: RNA-binding protein with multiple splicing (RBPMS); Recombinant Human RNA-binding protein with multiple splicing (RBPMS); RBPMS recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-196aa; Full Length
• Sequence: MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGTPNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYPASLHAQMRWLPPSEATSQGWKSRQFC
• Sequence Length: 196

• Species: Human
• Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for RBPMS recombinant protein

This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM domain consists of two short stretches of conserved sequence called RNP1 and RNP2, as well as a few highly conserved hydrophobic residues. This protein has a single, putative RRM domain in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI and Uniprot Product Information

• NCBI GI #: 57164969
• NCBI GeneID: 11030
• NCBI Accession #: NP_001008710.1
• NCBI GenBank Nucleotide #: NM_001008710.2
• UniProt Accession #: Q93062; Q92516; Q92517; Q92518; Q96J26; D3DSU9
• Molecular Weight: 28.8 kDa
• NCBI Official Full Name: RNA-binding protein with multiple splicing isoform A
• NCBI Official Synonym Full Names: RNA binding protein, mRNA processing factor
• NCBI Official Symbol: RBPMS
• NCBI Official Synonym Symbols: HERMES
• NCBI Protein Information: RNA-binding protein with multiple splicing
• UniProt Protein Name: RNA-binding protein with multiple splicing
• Protein Family: RNA-binding protein with multiple splicing
• UniProt Gene Name: RBPMS
• UniProt Synonym Gene Names: HERMES; RBP-MS; Hermes

NCBI Description

This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Uniprot Description

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins (PubMed:26347403). Binds to poly(A) RNA (PubMed:17099224, PubMed:26347403).