Rat Vitamin K1 (VK1) ELISA Kit | VK1 elisa kit

Rat Vitamin K1 (VK1) ELISA kit

Cat. Num. AAA266013

• Reactivity: Rat
• Synonyms: Vitamin K1 (VK1); Rat Vitamin K1 (VK1) ELISA kit; VK1 elisa kit

• Reactivity: Rat
• Sequence Length: 161

• Preparation and Storage: Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 42627871
• NCBI GeneID: 309004
• NCBI Accession #: NP_976080.1
• NCBI GenBank Nucleotide #: NM_203335.2
• Molecular Weight: 17,783 Da
• NCBI Official Full Name: vitamin K epoxide reductase complex subunit 1
• NCBI Official Synonym Full Names: vitamin K epoxide reductase complex, subunit 1
• NCBI Official Symbol: Vkorc1
• NCBI Protein Information: vitamin K epoxide reductase complex subunit 1; Warfarin resistance; phylloquinone epoxide reductase; vitamin K1 2,3-epoxide reductase subunit 1; vitamin K1 epoxide reductase (warfarin-sensitive)
• UniProt Protein Name: Vitamin K epoxide reductase complex subunit 1
• UniProt Gene Name: Vkorc1
• UniProt Entry Name: VKOR1_RAT

NCBI Description

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.