Rat Vitamin K1 ELISA Kit | Vkorc1 elisa kit

Rat Vitamin K1 ELISA Kit

Cat. Num. AAA3809248

• Reactivity: Rat
• Synonyms: Vitamin K1; Rat Vitamin K1 ELISA Kit; Vkorc1 elisa kit

• Reactivity: Rat
• Sequence Length: 161

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 400 pg/ml-6400 pg/ml
• Sensitivity: 10 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Vkorc1 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofVITAMIN K1in the sample, This VITAMIN K1ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusVITAMIN K1concentration. The concentration ofVITAMIN K1in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 42627871
• NCBI GeneID: 309004
• NCBI Accession #: NP_976080.1
• NCBI GenBank Nucleotide #: NP_976080.1
• UniProt Accession #: Q6TEK4
• NCBI Official Full Name: vitamin K epoxide reductase complex subunit 1
• NCBI Official Synonym Full Names: vitamin K epoxide reductase complex, subunit 1
• NCBI Official Symbol: Vkorc1
• NCBI Protein Information: vitamin K epoxide reductase complex subunit 1
• UniProt Protein Name: Vitamin K epoxide reductase complex subunit 1
• Protein Family: Vitamin K epoxide reductase complex
• UniProt Gene Name: Vkorc1
• UniProt Entry Name: VKOR1_RAT

NCBI Description

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. [provided by RefSeq, Jul 2008]