Typical Testing Data/Standard Curve (for reference only)
Rat Ras-related Protein Rab-3A, RAB3A ELISA Kit | RAB3A elisa kit
Rat Ras-related Protein Rab-3A, RAB3A ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Rat RAB3A antibody. RAB3A present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat RAB3A Antibody is added and binds to RAB3A in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated RAB3A antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat RAB3A. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
Uniprot Description
RAB3A: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A. Interacts with the exocyst complex through SEC15. Binds SYTL4, RIMS1 and RIMS2. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3. Specifically expressed in brain. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein; G protein, monomeric, Rab; G protein, monomeric
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: synaptic vesicle; protein complex; secretory granule membrane; axon; acrosome; plasma membrane; terminal button; cytosol; vesicle; endosome
Molecular Function: GTPase activity; protein C-terminus binding; protein binding; GTPase binding; ATPase activator activity; GDP binding; GTP binding; myosin V binding; ATPase binding
Biological Process: mitochondrion organization and biogenesis; synaptic vesicle maturation; metabolic process; neurotransmitter secretion; regulation of synaptic vesicle fusion to presynaptic membrane; constitutive secretory pathway; protein secretion; regulation of short-term neuronal synaptic plasticity; post-embryonic development; respiratory system process; intracellular protein transport; synaptic transmission; synaptic vesicle exocytosis; axonogenesis; glutamate secretion; sensory perception of touch; positive regulation of ATPase activity; neuromuscular synaptic transmission; maintenance of presynaptic active zone structure; response to electrical stimulus; Rab protein signal transduction; vesicle docking during exocytosis; positive regulation of exocytosis; lung development
Research Articles on RAB3A
Similar Products
Product Notes
The Rat RAB3A rab3a (Catalog #AAA1604116) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1604116 ELISA Kit recognizes Rat RAB3A. It is sometimes possible for the material contained within the vial of "Ras-related Protein Rab-3A, RAB3A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
