Typical Testing Data/Standard Curve (for reference only)
Rat Proto-oncogene c-Fos ELISA Kit | Fos elisa kit
Rat Proto-oncogene c-Fos ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to Proto-oncogene c-Fos. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody preparation specific for Proto-oncogene c-Fos and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain Proto-oncogene c-Fos, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The concentration of Proto-oncogene c-Fos in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
an immediate early gene encoding a nuclear protein involved in signal transduction [RGD, Feb 2006]
Uniprot Description
Fos: a proto-oncogenic transcription factor of the bZIP family. Dimerizes with proteins of the JUN family, thereby forming the transcription factor complex AP-1. FOS proteins function as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of FOS has also been associated with apoptotic cell death. Expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 6q31
Cellular Component: membrane; neuron projection; nucleoplasm; nucleus; transcription factor complex
Molecular Function: chromatin binding; DNA binding; double-stranded DNA binding; protein binding; protein heterodimerization activity; sequence-specific DNA binding; transcription factor activity; transcription factor binding
Biological Process: aging; cellular response to extracellular stimulus; cellular response to hormone stimulus; conditioned taste aversion; female pregnancy; nervous system development; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; response to cAMP; response to cold; response to corticosterone stimulus; response to cytokine stimulus; response to drug; response to gravity; response to light stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to organic cyclic substance; response to progesterone stimulus; response to toxin; sleep; transcription from RNA polymerase II promoter; transforming growth factor beta receptor signaling pathway
Research Articles on Fos
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Product Notes
The Rat Fos fos (Catalog #AAA9426978) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9426978 ELISA Kit recognizes Rat Fos. It is sometimes possible for the material contained within the vial of "Proto-oncogene c-Fos, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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