Rat Pleiotrophin (PTN) ELISA Kit | PTN elisa kit

Rat Pleiotrophin (PTN) ELISA Kit

Cat. Num. AAA454056

• Gene Names: Ptn; HARP; Hbnf
• Reactivity: Rat
• Synonyms: Pleiotrophin (PTN); Rat Pleiotrophin (PTN) ELISA Kit; Thyroid peroxidase; Tpo; PTN elisa kit

• Reactivity: Rat
• Sequence Length: 168

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 31.25-2000pg/mL
• Sensitivity: 12.5pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 8394103
• NCBI GeneID: 24924
• NCBI Accession #: NP_058762.1
• NCBI GenBank Nucleotide #: NM_017066.2
• UniProt Accession #: P63090; P20935
• Molecular Weight: 18,869 Da
• NCBI Official Full Name: pleiotrophin
• NCBI Official Synonym Full Names: pleiotrophin
• NCBI Official Symbol: Ptn
• NCBI Official Synonym Symbols: HARP; Hbnf
• NCBI Protein Information: pleiotrophin
• UniProt Protein Name: Pleiotrophin
• Protein Family: Pleiotrophin
• UniProt Gene Name: Ptn
• UniProt Synonym Gene Names: PTN; HBBM; HBGF-8; HB-GAM; HBNF; OSF-1

NCBI Description

binds heparin; may act as a growth factor; may play a role in liver regeneration and fibrinogenesis [RGD, Feb 2006]

Uniprot Description

Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. Binds to cell-surface target proteins via their chondroitin sulfate groups (). Down-regulates PTPRZ1 activity (PubMed:16814777).