Rat Pigment Epithelium Derived Factor (PEDF) ELISA Kit | PEDF elisa kit
Rat Pigment Epithelium Derived Factor (PEDF) Mini Samples ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
mouse homolog is a proteinase inhibitor involved in vascularization [RGD, Feb 2006]
Uniprot Description
PEDF: a secreted neurotrophic protein that induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The N-terminal (AA 44-121) exhibits neurite outgrowth-inducing activity. The C-terminal exposed loop (AA 382-418) is essential for serpin activity. Extracellular phosphorylation enhances antiangiogenic activity.
Protein type: Inhibitor; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q24
Cellular Component: axon; axon hillock; basement membrane; cell soma; extracellular matrix; extracellular region; extracellular space; perinuclear region of cytoplasm
Molecular Function: serine-type endopeptidase inhibitor activity
Biological Process: aging; kidney development; negative regulation of angiogenesis; negative regulation of inflammatory response; ovulation cycle; positive regulation of neurogenesis; response to acidity; response to arsenic; retina development in camera-type eye; short-term memory
Research Articles on PEDF
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Product Notes
The Rat PEDF serpinf1 (Catalog #AAA2087938) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2087938 ELISA Kit recognizes Rat PEDF. It is sometimes possible for the material contained within the vial of "Pigment Epithelium Derived Factor (PEDF), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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