Typical Testing Data/Standard Curve (for reference only)
Rat CCL11 ELISA Kit | CCL11 elisa kit
Rat CCL11 ELISA Kit
Gene Names
Ccl11; Scya11
Reactivity
Rat
Synonyms
CCL11; Rat CCL11 ELISA Kit; SCYA11; Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11; CCL11 elisa kit
Reactivity
Rat
Specificity
The Rat CCL11 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Rat CCL11 proteins within the range of 15.6 pg/ml - 1000 pg/ml.
Sequence Length
97
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<10 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for CCL11 elisa kit
Principle of the Assay: The Rat CCL11 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat CCL11 in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Rat CCL11 coated on a 96-well plate. Standards and samples are pipetted into the wells and CCL11 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Rat CCL11 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CCL11 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Eotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin.
Background: Eotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,851 Da
NCBI Official Full Name
eotaxin
NCBI Official Synonym Full Names
C-C motif chemokine ligand 11
NCBI Official Symbol
Ccl11
NCBI Official Synonym Symbols
Scya11
NCBI Protein Information
eotaxin
UniProt Protein Name
Eotaxin
Protein Family
UniProt Gene Name
Ccl11
UniProt Synonym Gene Names
Scya11
UniProt Entry Name
CCL11_RAT
NCBI Description
mouse homolog is an eosinophil chemoattractant [RGD, Feb 2006]
Uniprot Description
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions.
Research Articles on CCL11
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Product Notes
The Rat CCL11 ccl11 (Catalog #AAA8248471) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8248471 ELISA Kit recognizes Rat CCL11. It is sometimes possible for the material contained within the vial of "CCL11, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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