Rat Apoptosis-Associated Speck-Like Protein Containing A CARD ELISA Kit | pycard elisa kit

Rat Apoptosis-Associated Speck-Like Protein Containing A CARD ELISA Kit

Cat. Num. AAA3809786

• Gene Names: pycard; ASC; asc1; zAsc; zgc:109874
• Reactivity: Rat
• Synonyms: Apoptosis-Associated Speck-Like Protein Containing A CARD; Rat Apoptosis-Associated Speck-Like Protein Containing A CARD ELISA Kit; pycard elisa kit

• Reactivity: Rat
• Sequence Length: 203

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 31.25 pg/ml-500 pg/ml
• Sensitivity: 1 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for pycard elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofAPOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARDin the sample, This APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARDELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusAPOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARDconcentration. The concentration ofAPOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARDin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 18203023
• NCBI GeneID: 57923
• UniProt Accession #: Q9I9N6
• NCBI Official Full Name: Apoptosis-associated speck-like protein containing a CARD
• NCBI Official Synonym Full Names: PYD and CARD domain containing
• NCBI Official Symbol: pycard
• NCBI Official Synonym Symbols: ASC; asc1; zAsc; zgc:109874
• NCBI Protein Information: apoptosis-associated speck-like protein containing a CARD
• UniProt Protein Name: Apoptosis-associated speck-like protein containing a CARD
• Protein Family: Apoptosis-associated speck-like protein
• UniProt Gene Name: pycard
• UniProt Synonym Gene Names: asc; asc1

Uniprot Description

Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis. Induces proteolytic processing of caspa and caspa-dependent apoptosis. In innate immune response believed to act as an integral adapter in the assembly of the inflammasome which activates a caspase leading to processing and secretion of proinflammatory cytokines. The function as activating adapter in different types of inflammasomes is mediated by the pyrin and CARD domains and their homotypic interactions. Also involved in transcriptional activation of cytokines and chemokines independent of the inflammasome.