Rat Androgen Receptor (AR) ELISA Kit | AR elisa kit

Rat Androgen Receptor (AR) ELISA Kit

Cat. Num. AAA3808424

• Gene Names: Ar; Tfm; AW320017
• Reactivity: Rat
• Synonyms: Androgen Receptor (AR); Rat Androgen Receptor (AR) ELISA Kit; AR elisa kit

• Reactivity: Rat
• Sequence Length: 899

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 25 pg/ml-400 pg/ml
• Sensitivity: 1 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for AR elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofARin the sample, This ARELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusARconcentration. The concentration ofARin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 7304901
• NCBI GeneID: 11835
• NCBI Accession #: NP_038504.1
• NCBI GenBank Nucleotide #: NP_038504.1
• UniProt Accession #: P19091
• NCBI Official Full Name: androgen receptor
• NCBI Official Synonym Full Names: androgen receptor
• NCBI Official Symbol: Ar
• NCBI Official Synonym Symbols: Tfm; AW320017
• NCBI Protein Information: androgen receptor
• UniProt Protein Name: Androgen receptor
• Protein Family: Allatostatin
• UniProt Gene Name: Ar
• UniProt Synonym Gene Names: Nr3c4

NCBI Description

This gene encodes a nuclear hormone receptor containing zinc finger and DNA-binding domains. The encoded protein is a key regulator of signalling by androgens, a class of steroid hormones involved in male reproductive development. The protein responds to hormone signalling by translocating to the nucleus, forming dimers, and binding to androgen response elements (AREs) in the promoters of target genes, which are subsequently transcriptionally activated. Activity of this protein is negatively regulated by nuclear receptor subfamily 0 group B member 1 (Nr0b1, also known as Dax1). Mutations in this gene result in feminized genitals and infertility in male animals. Loss of function in female animals also causes problems in reproductive development and function. [provided by RefSeq, May 2015]

Uniprot Description

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.