Prostaglandin F2 Receptor Negative Regulator Recombinant Protein | PTGFRN recombinant protein

Recombinant Prostaglandin F2 Receptor Negative Regulator (PTGFRN)

Cat. Num. AAA2033582

• Gene Names: PTGFRN; FPRP; CD315; EWI-F; CD9P-1; SMAP-6
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 90%
• Synonyms: Prostaglandin F2 Receptor Negative Regulator; Recombinant Prostaglandin F2 Receptor Negative Regulator (PTGFRN); CD315; CD9P-1; EWI-F; FPRP; SMAP-6; CD9 partner 1; Glu-Trp-Ile EWI motif-containing protein F; Prostaglandin F2-alpha receptor-associated protein; PTGFRN recombinant protein

• Host: E Coli
• Purity/Purification: > 90%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: PDYQV YLNASKVPGF ADDPTELACR VVDTKSGEAN VRFTVSWYYRMNRRSDNVVT SELLAVMDGD WTLKYGERSK QRAQDGDFIF SKEHTDTFNFRIQRTTEEDR GNYYCVVSAW TKQRNNSWVK SKDVFSKPVN IFWALEDSVLVVKARQPKPF FAAGNTFEMT CKVSSKNIKS PRYSVLIMAE KPVGDLSSPNETKYIISLDQ DSVVKLENWT DASRVDGVVL EKVQEDEFRY RMYQTQVSDAGLYRCMVTAW SP
• Sequence Length: 879

• Applicable Applications for PTGFRN recombinant protein: SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP).
• Predicted Molecular Mass: 33.3kDa
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Endotoxin Level: <1.0EU per 1 ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Fragment: Pro406~Pro662
• Organism Species: Human
• Tag: two N-terminal Tags, His-tag and T7-tag
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 41152506
• NCBI GeneID: 5738
• NCBI Accession #: NP_065173.2
• NCBI GenBank Nucleotide #: NM_020440.3
• Molecular Weight: 98,556 Da
• NCBI Official Full Name: prostaglandin F2 receptor negative regulator
• NCBI Official Synonym Full Names: prostaglandin F2 receptor inhibitor
• NCBI Official Symbol: PTGFRN
• NCBI Official Synonym Symbols: FPRP; CD315; EWI-F; CD9P-1; SMAP-6
• NCBI Protein Information: prostaglandin F2 receptor negative regulator
• UniProt Protein Name: Prostaglandin F2 receptor negative regulator
• Protein Family: Prostaglandin F2 receptor negative regulator
• UniProt Gene Name: PTGFRN
• UniProt Synonym Gene Names: CD9P1; EWIF; FPRP; KIAA1436; CD9P-1; EWI-F
• UniProt Entry Name: FPRP_HUMAN

Uniprot Description

PTGFRN: Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.

Protein type: Cytoskeletal; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: cell surface; endoplasmic reticulum membrane; Golgi apparatus; integral to membrane

Molecular Function: protein binding