Rat IGFBP6 (Insulin Like Growth Factor Binding Protein 6) CLIA Kit | IGFBP6 clia kit

Rat IGFBP6 (Insulin Like Growth Factor Binding Protein 6) CLIA Kit

Cat. Num. AAA2532112

• Gene Names: IGFBP6; IBP6
• Reactivity: Rat
• Synonyms: IGFBP6 (Insulin Like Growth Factor Binding Protein 6); Rat IGFBP6 (Insulin Like Growth Factor Binding Protein 6) CLIA Kit; IGFBP6 clia kit

• Reactivity: Rat
• Specificity: This kit recognizes natural and recombinant IGFBP6. No significant cross-reactivity or interference between IGFBP6 and analogues was observed.
• Sequence Length: 240

• Assay Type: Sandwich
• Detection Range: 31.25-2000pg/mL
• Sensitivity: Min: 18.75pg/mL; Max: 2000pg/mL

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for IGFBP6 clia kit

Intended Uses: This CLIA kit applies to the in vitro quantitative determination of IGFBP6 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to IGFBP6. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for IGFBP6 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain IGFBP6, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of IGFBP6. You can calculate the concentration of IGFBP6 in the samples by comparing the RLU value of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 11321593
• NCBI GeneID: 3489
• NCBI Accession #: NP_002169.1
• NCBI GenBank Nucleotide #: NM_002178.2
• Molecular Weight: 25,322 Da
• NCBI Official Full Name: insulin-like growth factor-binding protein 6
• NCBI Official Synonym Full Names: insulin-like growth factor binding protein 6
• NCBI Official Symbol: IGFBP6
• NCBI Official Synonym Symbols: IBP6
• NCBI Protein Information: insulin-like growth factor-binding protein 6
• UniProt Protein Name: Insulin-like growth factor-binding protein 6
• Protein Family: Insulin-like growth factor-binding protein
• UniProt Gene Name: IGFBP6
• UniProt Synonym Gene Names: IBP6; IBP-6; IGF-binding protein 6; IGFBP-6
• UniProt Entry Name: IBP6_HUMAN

Uniprot Description

IGFBP6: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Protein type: Secreted; Cell cycle regulation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: Golgi apparatus; extracellular space; extracellular region

Molecular Function: insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: negative regulation of cell proliferation; regulation of insulin-like growth factor receptor signaling pathway; cellular protein metabolic process; regulation of cell growth; signal transduction