Rat RAS p21 protein activator (GTPase activating protein) 1 ELISA Kit | RASA1 elisa kit
Rat Ras GTPase-activating protein 1, RASA1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
may play a role in Ras GTPase mediated signal transduction; may be involved in cell proliferation and cell migration [RGD, Feb 2006]
Uniprot Description
RASA1: a GTPase activator for normal RAS p21 but not its oncogenic counterpart, converting it to the putatively inactive GDP-bound state. Acting as a suppressor of RAS function, it enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Two alternatively spliced isoforms have been described.
Protein type: Motility/polarity/chemotaxis; Oncoprotein; GAPs; GAPs, Ras
Cellular Component: ruffle; cytoplasm; plasma membrane; intracellular
Molecular Function: protein binding; GTPase binding; glycoprotein binding; GTPase activator activity; receptor binding
Biological Process: regulation of actin filament polymerization; cytokinesis after mitosis; blood vessel morphogenesis; negative regulation of Ras protein signal transduction; negative regulation of cell adhesion; negative regulation of neuron apoptosis; cell adhesion; actin cytoskeleton organization and biogenesis; signal transduction; negative regulation of cell-matrix adhesion; vasculogenesis; positive regulation of GTPase activity
Research Articles on RASA1
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Product Notes
The Rat RASA1 rasa1 (Catalog #AAA9328380) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328380 ELISA Kit recognizes Rat RASA1. It is sometimes possible for the material contained within the vial of "RAS p21 protein activator (GTPase activating protein) 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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