Rabbit anti-Human, mouse BCL2L12 Antibody | anti-BCL2L12 antibody

Rabbit BCL2L12 Antibody

Cat. Num. AAA4764

• Reactivity: Human, mouse
• Applications: ELISA, Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: BCL2L12; Rabbit BCL2L12 Antibody; anti-BCL2L12 antibody

• Host: Rabbit
• Reactivity: Human, mouse
• Specificity: BCL2L12 antibody detects endogenous levels of total BCL2L12 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 333

• Applicable Applications for anti-BCL2L12 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500~1:1000 ; ELISA: 1:1000
• Preparation and Storage: Store at -20 degree C/1 year

Western Blot

(Western blot analysis of extracts from CoLo cells, using BCL2L12 antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 100913021
• NCBI GeneID: 83596
• NCBI Accession #: NP_001035758.1
• NCBI GenBank Nucleotide #: NM_001040668.1
• UniProt Accession #: Q9HB09; Q3SY11; Q3SY13; Q96I96; Q9HB08
• Molecular Weight: 36,821 Da
• NCBI Official Full Name: bcl-2-like protein 12 isoform 3
• NCBI Official Synonym Full Names: BCL2-like 12 (proline rich)
• NCBI Official Symbol: BCL2L12
• NCBI Protein Information: bcl-2-like protein 12; bcl2-L-12; Bcl-2 related proline-rich protein; bcl-2-related proline-rich protein
• UniProt Protein Name: Bcl-2-like protein 12
• Protein Family: Bcl-2-like protein
• UniProt Gene Name: BCL2L12
• UniProt Synonym Gene Names: BPR; Bcl2-L-12
• UniProt Entry Name: B2L12_HUMAN

NCBI Description

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

Bcl-2L12: belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: membrane; nucleus

Molecular Function: protein binding; p53 binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter