Rabbit Cyclin-related protein FAM58A (FAM58A) ELISA Kit | FAM58A elisa kit
Rabbit Cyclin-related protein FAM58A (FAM58A) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Uniprot Description
FAM58B: May have a role in cell proliferation. Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR); also known as STAR syndrome or syndactyly with renal and anogenital malformations. Belongs to the cyclin family. Cyclin-like FAM58 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: DNA-directed RNA polymerase II, holoenzyme
Molecular Function: protein binding; protein kinase binding; protein kinase activator activity
Biological Process: regulation of transcription, DNA-dependent; positive regulation of MAPKKK cascade; positive regulation of protein kinase activity; regulation of cyclin-dependent protein kinase activity
Disease: Toe Syndactyly, Telecanthus, And Anogenital And Renal Malformations
Research Articles on FAM58A
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Product Notes
The Rabbit FAM58A fam58a (Catalog #AAA7206488) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7206488 ELISA Kit recognizes Rabbit FAM58A. It is sometimes possible for the material contained within the vial of "Cyclin-related protein FAM58A (FAM58A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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