Western Blot (WB)
(Western blot analysis of FA58A expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.)
Rabbit FA58A Polyclonal Antibody | anti-FA58A antibody
FA58A Antibody
Western Blot (WB)
(Western blot analysis of FA58A expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of FA58A expression in HEK293 cells,The lane on the left is treated with the antigen-specific peptide.)
NCBI and Uniprot Product Information
NCBI Description
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Uniprot Description
FAM58B: May have a role in cell proliferation. Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR); also known as STAR syndrome or syndactyly with renal and anogenital malformations. Belongs to the cyclin family. Cyclin-like FAM58 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: cyclin-dependent protein kinase holoenzyme complex; nucleus
Molecular Function: cyclin-dependent protein kinase regulator activity; protein binding
Biological Process: positive regulation of cyclin-dependent protein kinase activity; positive regulation of transcription from RNA polymerase II promoter
Disease: Toe Syndactyly, Telecanthus, And Anogenital And Renal Malformations
Research Articles on FA58A
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Product Notes
The FA58A fam58a (Catalog #AAA9418114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FA58A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FA58A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:2000. Researchers should empirically determine the suitability of the FA58A fam58a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FA58A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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