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Rabbit CIDE-B (CT) Antibody | anti-CIDEB antibody

Anti-CIDE-B (CT) Antibody

Gene Names
CIDEB; CIDEB
Applications
Immunoblot, Western Blot
Synonyms
CIDE-B (CT); Anti-CIDE-B (CT) Antibody; Anti-CIDE-B (CT); mCIDE-B (mouse CT); anti-CIDEB antibody
Ordering
For Research Use Only!
Host
Rabbit
Specificity
Anti-CIDE-B (CT) [Rabbit antibody to peptide corresponding to aa 204-219 of mouse CIDE-B.]
This antibody recognizes mouse CIDEB (25kD). No cross-reactivity with CIDE-A.
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-CIDEB antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:1,000 dilution.
Positive control: Tissue lysate of mouse liver.
Antigen
Peptide corresponding to aa 204-219 of mouse CIDE-B.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-CIDEB antibody
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated Dnase. DFF45/ICAD has been identified as an inhibitor of caspase activated Dnase DFF40/CAD. DFF45-related proteins CIDE-A and CIDE-B have recently been identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.
Product Categories/Family for anti-CIDEB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24,678 Da
NCBI Official Full Name
Cide-b
NCBI Official Synonym Full Names
cell death-inducing DFFA-like effector b
NCBI Official Symbol
CIDEB
NCBI Official Synonym Symbols
CIDEB
NCBI Protein Information
cell death-inducing DFFA-like effector b
UniProt Protein Name
Cell death activator CIDE-B
Protein Family
UniProt Gene Name
CIDEB
UniProt Entry Name
CIDEB_HUMAN

Uniprot Description

CIDEB: Activates apoptosis.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: perinuclear region of cytoplasm; lipid particle; cytosol

Molecular Function: identical protein binding; protein binding

Biological Process: regulation of apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; apoptosis

Research Articles on CIDEB

Similar Products

Product Notes

The CIDEB cideb (Catalog #AAA194051) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CIDE-B (CT) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:1,000 dilution. Positive control: Tissue lysate of mouse liver. Researchers should empirically determine the suitability of the CIDEB cideb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIDE-B (CT), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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