Rabbit ARC (CT) Antibody | anti-ARC antibody
Anti-ARC (CT) Antibody
Gene Names
ARC; Arg3.1; KIAA0278; ARC
Applications
Immunoblot, Western Blot
Synonyms
ARC (CT); Anti-ARC (CT) Antibody; Anti-ARC (CT); anti-ARC antibody
Host
Rabbit
Specificity
Anti-ARC (CT) [Rabbit antibody to peptide corresponding to aa 191-208 at C-terminus of human apoptosis repressor with CARD (ARC).]
This antibody recognizes full-length ARC (25 kD).
This antibody recognizes full-length ARC (25 kD).
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-ARC antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:1,000 dilution.
Positive control: Whole cell lysate of HeLa, KB, and A549 cells.
Positive control: Whole cell lysate of HeLa, KB, and A549 cells.
Antigen
Peptide corresponding to aa 191-208 of human ARC.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-ARC antibody
Apoptosis is regulated by death domain (DD)- and/or caspase recruitment domain (CARD)-containing molecules and a caspase family of proteases. CARD domain-containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR- 1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Product Categories/Family for anti-ARC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
45,316 Da
NCBI Official Full Name
ARC
NCBI Official Synonym Full Names
activity-regulated cytoskeleton-associated protein
NCBI Official Symbol
ARC
NCBI Official Synonym Symbols
Arg3.1; KIAA0278; ARC
NCBI Protein Information
activity-regulated cytoskeleton-associated protein
UniProt Protein Name
Activity-regulated cytoskeleton-associated protein
Protein Family
UniProt Gene Name
ARC
UniProt Synonym Gene Names
KIAA0278
UniProt Entry Name
ARC_HUMAN
Uniprot Description
ARG3.1: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Belongs to the ARC/ARG3.1 family.
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: postsynaptic membrane; cytoplasm; postsynaptic density; dendritic spine; acrosome; plasma membrane; cell junction; endosome; actin cytoskeleton
Biological Process: anterior/posterior pattern formation; cell migration; regulation of cell morphogenesis; cytoskeleton organization and biogenesis; endocytosis; learning; endoderm development; regulation of neuronal synaptic plasticity
Similar Products
Product Notes
The ARC arc (Catalog #AAA194026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ARC (CT) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:1,000 dilution. Positive control: Whole cell lysate of HeLa, KB, and A549 cells. Researchers should empirically determine the suitability of the ARC arc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARC (CT), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
