SDS-Page
RAB3IL recombinant protein
RAB3IL, 1-382aa, Human, His tag, E.col
Gene Names
RAB3IL1; GRAB
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
RAB3IL; 1-382aa; Human; His tag; E.col; Guanine nucleotide exchange factor for Rab-3A isoform 1; GRAB; RAB3IL recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In phosphate buffer saline (pH 7.4) containing 50% glycerol
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMWSGPPQ PDQGLPPPLA AVPVPWKSTD PCQGHRESPG ALVETSAGEE AQGQEGPAAA QLDVLRLRSS SMEIREKGSE FLKEELHRAQ KELKLKDEEC ERLSKVREQL EQELEELTAS LFEEAHKMVR EANMKQAASE KQLKEARGKI DMLQAEVTAL KTLVITSTPA SPNRELHPQL LSPTKAGPRK GHSRHKSTSS TLCPAVCPAA GHTLTPDREG KEVDTILFAE FQAWRESPTL DKTCPFLERV YREDVGPCLD FTMQELSVLV RAAVEDNTLT IEPVASQTLP TVKVAEVDCS STNTCALSGL TRTCRHRIRL GDSKSHYYIS PSSRARITAV CNFFTYIRYI QQGLVRQDAE PMFWEIMRLR KEMSLAKLGF FPQEA
Sequence Length
382
Applicable Applications for RAB3IL recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for RAB3IL recombinant protein
Guanine nucleotide exchange factor for Rab-3A isoform 1, also known as RAB3IL, is a 382 amino acid protein that belongs to the SEC2 family. RAB3IL1 is a guanine nucleotide exchange factor (GEF) for Rab3A. RAB3IL1 competes for an interaction with Rab3A and IHPK1 through its coiled coil domain, which does not require IHPK1 kinase activity. Recombinant human RAB3IL1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for RAB3IL recombinant protein
References
Luo H R., et al. (2001) Neuron. 31: 439-451.; Rual J F., et al. (2005) Nature. 437: 1173-1178.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45kDa (405aa) confirmed by MALDI-TOF
NCBI Official Full Name
guanine nucleotide exchange factor for Rab-3A isoform 1
NCBI Official Synonym Full Names
RAB3A interacting protein like 1
NCBI Official Symbol
RAB3IL1
NCBI Official Synonym Symbols
GRAB
NCBI Protein Information
guanine nucleotide exchange factor for Rab-3A
UniProt Protein Name
Guanine nucleotide exchange factor for Rab-3A
UniProt Gene Name
RAB3IL1
UniProt Synonym Gene Names
Rab3A-interacting-like protein 1
NCBI Description
This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012]
Uniprot Description
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B.
Research Articles on RAB3IL
Similar Products
Product Notes
The RAB3IL rab3il1 (Catalog #AAA206043) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's RAB3IL can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the RAB3IL rab3il1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSMWSGPPQ PDQGLPPPLA AVPVPWKSTD PCQGHRESPG ALVETSAGEE AQGQEGPAAA QLDVLRLRSS SMEIREKGSE FLKEELHRAQ KELKLKDEEC ERLSKVREQL EQELEELTAS LFEEAHKMVR EANMKQAASE KQLKEARGKI DMLQAEVTAL KTLVITSTPA SPNRELHPQL LSPTKAGPRK GHSRHKSTSS TLCPAVCPAA GHTLTPDREG KEVDTILFAE FQAWRESPTL DKTCPFLERV YREDVGPCLD FTMQELSVLV RAAVEDNTLT IEPVASQTLP TVKVAEVDCS STNTCALSGL TRTCRHRIRL GDSKSHYYIS PSSRARITAV CNFFTYIRYI QQGLVRQDAE PMFWEIMRLR KEMSLAKLGF FPQEA. It is sometimes possible for the material contained within the vial of "RAB3IL, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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