Protease Serine 3 Recombinant Protein | PRSS3 recombinant protein

Recombinant Human Protease Serine 3

Cat. Num. AAA146366

• Gene Names: PRSS3; T9; MTG; TRY3; TRY4; PRSS4
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: Protease Serine 3; Recombinant Human Protease Serine 3; PRSS3 Human; Protease Serine 3 Human Recombinant; Protease Serine 3 (Mesotrypsin); Protease Serine 4 (Trypsin 4; Brain); Brain Trypsinogen; Mesotrypsinogen; Trypsin III; Trypsinogen IV; Trypsinogen 5; Pancreatic Trypsinogen III; MTG; TRY3; PRSS4; T9; EC 3.4.21; PRSS3 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: The PRSS3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.; Sterile filtered colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSIVGGYTC EENSLPYQVS LNSGSHFCGG SLISEQWVVS AAHCYKTRIQ VRLGEHNIKV LEGNEQFINA AKIIRHPKYN RDTLDNDIML IKLSSPAVIN ARVSTISLPT APPAAGTECL ISGWGNTLSF GADYPDELKC LDAPVLTQAE CKASYPGKIT NSMFCVGFLE GGKDSCQRDS GGPVVCNGQL QGVVSWGHGC AWKNRPGVYT KVYNYVDWIK DTIAANS
• Sequence Length: 261

• Preparation and Storage: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Related Product Information for PRSS3 recombinant protein

Description: PRSS3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 247 amino acids (81-304) and having a molecular mass of 26.0kDa.PRSS3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: PRSS3 is a trypsinogen, and a member of the trypsin family of serine proteases. PRSS3 is expressed in the pancreas and brain and is unaffected by common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. PRSS3 is restricted to the locus of T cell receptor beta variable orphans on chromosome 9. 4 different isoforms encoded by 4 transcript variants were identified for this gene.

Product Categories/Family for PRSS3 recombinant protein

Enzymes; Protease

NCBI and Uniprot Product Information

• NCBI GI #: 342672030
• NCBI GeneID: 5646
• NCBI Accession #: NP_001184026.2
• NCBI GenBank Nucleotide #: NM_001197097.2
• UniProt Accession #: P35030; P15951; Q15665; Q5VXV0; Q6ISJ4; Q9UQV3; A8CED1; A8CED3; A9Z1Y4; E7ES07; F8W7P3
• Molecular Weight: 25,924 Da
• NCBI Official Full Name: trypsin-3 isoform 3 preproprotein
• NCBI Official Synonym Full Names: protease, serine, 3
• NCBI Official Symbol: PRSS3
• NCBI Official Synonym Symbols: T9; MTG; TRY3; TRY4; PRSS4
• NCBI Protein Information: trypsin-3; brain trypsinogen; mesotrypsin; mesotrypsinogen; pancreatic trypsinogen III; protease, serine, 4 (trypsin 4, brain); trypsin III; trypsin IV; trypsinogen 4; trypsinogen 5; trypsinogen IV
• UniProt Protein Name: Trypsin-3
• UniProt Gene Name: PRSS3
• UniProt Synonym Gene Names: PRSS4; TRY3; TRY4
• UniProt Entry Name: TRY3_HUMAN

NCBI Description

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]

Uniprot Description

trypsin 3: Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5. Belongs to the peptidase S1 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; EC 3.4.21.4; Protease; Calcium-binding

Chromosomal Location of Human Ortholog: 9p11.2

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity; calcium ion binding

Biological Process: vitamin metabolic process; cobalamin metabolic process; digestion; innate immune response; endothelial cell migration; zymogen activation; proteolysis; water-soluble vitamin metabolic process