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PRS (Prolyl-tRNA Synthetase) Recombinant Protein | PRS recombinant protein
PRS (Prolyl-tRNA Synthetase)
Purity
>99%Multi-Step Chromatography
Synonyms
PRS (Prolyl-tRNA Synthetase); Prolyl tRNA Synthetase Protein; PRS recombinant protein
Host
E Coli
Purity/Purification
>99%
Multi-Step Chromatography
Multi-Step Chromatography
Form/Format
1X PBS (pH7.2) 200mM NaCl 20% Glycerol
Concentration
0.50 mg/ml (varies by lot)
Sequence Length
Full Length
Source
Human
Conjugation/Tag
N-term 6XHis tag
Preparation and Storage
Store at -70 degree C.
SDS-Page
SDS-Page
Related Product Information for PRS recombinant protein
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.
References
1. Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. Jonghyeon Son et al., Acta Cryst., Vol.D69, 2136-2145, 2013. 2. Lysine acetylation targets protein complexes and coregulates major cellular functions. Choudhary C. et al., Science, Vol.325, 834-840, 2009. 3. Evolution of acceptor stem tRNA recognition by class II prolyl-tRNA synthetase. Songon An et al., Nucleic Acids Research, Vol.36(8), 2514-2521, 2008. 4. Pre-transfer Editing by Class II Prolyl-tRNA Synthetase ROLE OF AMINOACYLATION ACTIVE SITE IN "SELECTIVE RELEASE" OF NONCOGNATE AMINO ACIDS. Sanchita Hati et al., THE JOURNAL OF BIOLOGICAL CHEMISTRY, Vol.281(38), 27862-27872, 2006.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58kDa
NCBI Official Full Name
prolyl-tRNA synthetase
NCBI Official Symbol
DQ04_00171080
NCBI Protein Information
prolyl-tRNA synthetase
Protein Family
Similar Products
Product Notes
The PRS (Catalog #AAA490326) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PRS (Prolyl-tRNA Synthetase), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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