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Prostaglandin D2 Synthase Recombinant Protein | PTGDS recombinant protein

Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His Tag)

Gene Names
Ptgds; PGD2; PGDS; 21kDa; PGDS2; Ptgs3; L-PGDS
Purity
>95% as determined by SDS-PAGE
Synonyms
Prostaglandin D2 Synthase; Prostaglandin D2 Synthase Protein; Mouse; Recombinant (His Tag); Mouse PTGDS/L-PGDS Protein (His Tag); 21kDa Protein; L-PGDS Protein; PGD2 Protein; PGDS Protein; PGDS2 Protein; Ptgs3 Protein; prostaglandin D2 synthase 21kDa (brain); PTGDS recombinant protein
Ordering
For Research Use Only!
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Glu189
Species
Mouse
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Gln 25
Tag
C-His
Protein Construction
A DNA sequence encoding the mouse Ptgds (NP_032989.2)(Met1-Glu189) was expressed with a polyhistidine tag at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.

SDS-Page

SDS-Page
Related Product Information for PTGDS recombinant protein
Background: PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2. It is involved in smooth muscle contraction/relaxation and a variety of central nervous system functions. PTGDS may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Product Categories/Family for PTGDS recombinant protein
References
Aebersold R, et al. (1993) Identification of a brain-specific human cerebrospinal fluid glycoprotein, beta-trace protein. Theor Electrophor. 3:229-234.Oliver K, et al. (2004) DNA sequence and analysis of human chromosome 9. Nature. 429:369-374.Bonaldo MF, et al. (1997) Normalization and subtraction: two approaches to facilitate gene discovery. Genome Res. 6(9):791-806.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,941 Da
NCBI Official Full Name
prostaglandin-H2 D-isomerase
NCBI Official Synonym Full Names
prostaglandin D2 synthase (brain)
NCBI Official Symbol
Ptgds
NCBI Official Synonym Symbols
PGD2; PGDS; 21kDa; PGDS2; Ptgs3; L-PGDS
NCBI Protein Information
prostaglandin-H2 D-isomerase

Research Articles on PTGDS

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Product Notes

The PTGDS (Catalog #AAA8123217) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Glu18 9. It is sometimes possible for the material contained within the vial of "Prostaglandin D2 Synthase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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