Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA) Recombinant Protein | PRKRA recombinant protein
Recombinant Human Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA) Protein
NCBI and Uniprot Product Information
Uniprot Description
PACT: a double strand RNA binding protein (dsRBP). Interacts with TRBP and Dicer to stimulate the cleavage of double-stranded or short hairpin RNA to siRNA. Appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. Activates the interferon-induced protein kinase PKR. Three alternatively spliced human isoforms have been reported.
Protein type: Activator; RNA processing; RNA-binding
Chromosomal Location of Human Ortholog: 2|2 C3
Cellular Component: cytoplasm; intracellular; membrane; nucleoplasm
Molecular Function: double-stranded RNA binding; enzyme binding; identical protein binding; protein binding; protein homodimerization activity; protein kinase binding
Biological Process: middle ear morphogenesis; miRNA-mediated gene silencing, production of miRNAs; outer ear morphogenesis; positive regulation of cell proliferation; pre-microRNA processing; protein amino acid phosphorylation; RNA interference, production of siRNA; skeletal morphogenesis
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Product Notes
The PRKRA prkra (Catalog #AAA286514) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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