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Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA) Recombinant Protein | PRKRA recombinant protein

Recombinant Human Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA) Protein

Purity
> 90% as determined by SDS-PAGE
Synonyms
Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA); Recombinant Human Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA) Protein; PRKRA ; DYT16; PACT; RAX; PKR; PRKRA recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 90% as determined by SDS-PAGE
Form/Format
Lyophilized or Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
678

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
34,371 Da
NCBI Official Full Name
Interferon-inducible double stranded RNA-dependent protein kinase activator A
UniProt Protein Name
Interferon-inducible double-stranded RNA-dependent protein kinase activator A
UniProt Gene Name
Prkra
UniProt Synonym Gene Names
Rax; RAX

Uniprot Description

PACT: a double strand RNA binding protein (dsRBP). Interacts with TRBP and Dicer to stimulate the cleavage of double-stranded or short hairpin RNA to siRNA. Appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor. Activates the interferon-induced protein kinase PKR. Three alternatively spliced human isoforms have been reported.

Protein type: Activator; RNA processing; RNA-binding

Chromosomal Location of Human Ortholog: 2|2 C3

Cellular Component: cytoplasm; intracellular; membrane; nucleoplasm

Molecular Function: double-stranded RNA binding; enzyme binding; identical protein binding; protein binding; protein homodimerization activity; protein kinase binding

Biological Process: middle ear morphogenesis; miRNA-mediated gene silencing, production of miRNAs; outer ear morphogenesis; positive regulation of cell proliferation; pre-microRNA processing; protein amino acid phosphorylation; RNA interference, production of siRNA; skeletal morphogenesis

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Product Notes

The PRKRA prkra (Catalog #AAA286514) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Interferon-inducible double stranded RNA-dependent protein kinase activator A (PRKRA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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