Mouse phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 1 ELISA Kit | PREX1 elisa kit
Mouse Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 1 protein, PREX1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PREX1: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. Interacts preferentially with RAC2. Interacts with RAC1. Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs, Rac/Rho; GEFs
Cellular Component: growth cone; membrane; intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasm; plasma membrane; dendritic shaft; cytosol
Molecular Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; phospholipid binding
Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; regulation of actin filament polymerization; positive regulation of cell adhesion; regulation of Rho protein signal transduction; regulation of dendrite development; positive regulation of GTPase activity; T cell differentiation
Research Articles on PREX1
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Product Notes
The Mouse PREX1 prex1 (Catalog #AAA9339412) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339412 ELISA Kit recognizes Mouse PREX1. It is sometimes possible for the material contained within the vial of "phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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