Mouse Peroxisome proliferator-activated receptor alpha ELISA Kit | Ppara elisa kit
Mouse Peroxisome proliferator-activated receptor alpha ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PPAR-alpha: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. Belongs to the nuclear hormone receptor family. NR1 subfamily.
Protein type: DNA-binding; Nuclear receptor
Cellular Component: nucleus
Molecular Function: DNA binding; drug binding; ligand-dependent nuclear receptor activity; lipid binding; metal ion binding; NFAT protein binding; phosphatase binding; protein binding; protein complex binding; protein domain specific binding; protein heterodimerization activity; receptor activity; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor activity; ubiquitin conjugating enzyme binding; zinc ion binding
Biological Process: behavioral response to nicotine; circadian regulation of gene expression; epidermis development; fatty acid metabolic process; glucose metabolic process; intracellular receptor-mediated signaling pathway; lipid metabolic process; lipoprotein metabolic process; negative regulation of appetite; negative regulation of blood pressure; negative regulation of inflammatory response; negative regulation of protein binding; negative regulation of transcription from RNA polymerase II promoter; positive regulation of fatty acid oxidation; positive regulation of gluconeogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of circadian rhythm; regulation of fatty acid metabolic process; regulation of gene expression; regulation of transcription, DNA-dependent; response to hypoxia; response to insulin stimulus; rhythmic process; steroid hormone mediated signaling; transcription, DNA-dependent; wound healing
Research Articles on Ppara
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Product Notes
The Mouse Ppara ppara (Catalog #AAA2884614) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884614 ELISA Kit recognizes Mouse Ppara. It is sometimes possible for the material contained within the vial of "Peroxisome proliferator-activated receptor alpha, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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