POU Class 6 Homeobox 1 Recombinant Protein | POU6F1 recombinant protein
Recombinant Human POU Class 6 Homeobox 1
Gene Names
POU6F1; BRN5; MPOU; TCFB1
Purity
Greater than 85% as determined by SDS-PAGE.
Synonyms
POU Class 6 Homeobox 1; Recombinant Human POU Class 6 Homeobox 1; POU6F1 Human; POU Class 6 Homeobox 1 Human Recombinant; BRN5; MPOU; TCFB1; Brain-5; Brn-5; mPOU homeobox protein; Brain-specific homeobox/POU domain protein 5; POU6F1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Form/Format
The POU5F1 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMPGISSQ ILTNAQGQVI GTLPWVVNSA SVAAPAPAQS LQVQAVTPQL LLNAQGQVIA TLASSPLPPP VAVRKPSTPE SPAKSEVQPI QPTPTVPQPA VVIASPAPAA KPSASAPIPI TCSETPTVSQ LVSKPHTPSL DEDGINLEEI REFAKNFKIR RLSLGLTQTQ VGQALTATEG PAYSQSAICR FEKLDITPKS AQKLKPVLEK WLNEAELRNQ EGQQNLMEFV GGEPSKKRKR RTSFTPQAIE ALNAYFEKNP LPTGQEITEI AKELNYDREV VRVWFCNRRQ TLKNTSKLNV FQIP
Sequence Length
301
Related Product Information for POU6F1 recombinant protein
Description: POU6F1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 324 amino acids (1-301 a.a.) and having a molecular mass of 35kDa.POU6F1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: POU6F1 is a member of the POU transcription factor family. POU6F1 is transcription factor that binds favorably to a variant of the octamer motif (5'-ATGATAAT-3'). POU6F1 is exclusively expressed in the embryo in the developing brain, however in the adult its expression is confined to the brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.
Introduction: POU6F1 is a member of the POU transcription factor family. POU6F1 is transcription factor that binds favorably to a variant of the octamer motif (5'-ATGATAAT-3'). POU6F1 is exclusively expressed in the embryo in the developing brain, however in the adult its expression is confined to the brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.
Product Categories/Family for POU6F1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,645 Da
NCBI Official Full Name
POU domain, class 6, transcription factor 1
NCBI Official Synonym Full Names
POU class 6 homeobox 1
NCBI Official Symbol
POU6F1
NCBI Official Synonym Symbols
BRN5; MPOU; TCFB1
NCBI Protein Information
POU domain, class 6, transcription factor 1; brain-5; brain-specific homeobox/POU domain protein 5; brn-5; mPOU homeobox protein
UniProt Protein Name
POU domain, class 6, transcription factor 1
Protein Family
UniProt Gene Name
POU6F1
UniProt Synonym Gene Names
BRN5; MPOU; TCFB1; Brain-5; Brn-5
UniProt Entry Name
PO6F1_HUMAN
Uniprot Description
POU6F1: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3'). Belongs to the POU transcription factor family. Class- 6 subfamily.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: nucleoplasm; nucleus; actin cytoskeleton
Molecular Function: DNA binding; transcription factor activity
Biological Process: muscle development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; heart development; brain development
Research Articles on POU6F1
1. POU6F1 siRNA dose-dependently suppressed the proliferation of clear cell adenocarcinoma cell lines.
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Product Notes
The POU6F1 pou6f1 (Catalog #AAA146431) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMPG ISSQ ILTNAQGQVI GTLPWVVNSA SVAAPAPAQS LQVQAVTPQL LLNAQGQVIA TLASSPLPPP VAVRKPSTPE SPAKSEVQPI QPTPTVPQPA VVIASPAPAA KPSASAPIPI TCSETPTVSQ LVSKPHTPSL DEDGINLEEI REFAKNFKIR RLSLGLTQTQ VGQALTATEG PAYSQSAICR FEKLDITPKS AQKLKPVLEK WLNEAELRNQ EGQQNLMEFV GGEPSKKRKR RTSFTPQAIE ALNAYFEKNP LPTGQEITEI AKELNYDREV VRVWFCNRRQ TLKNTSKLNV FQIP. It is sometimes possible for the material contained within the vial of "POU Class 6 Homeobox 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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