POU domain, class 4, transcription factor 2 (POU4F2) Recombinant Protein | POU4F2 recombinant protein
Recombinant Human POU domain, class 4, transcription factor 2 (POU4F2)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]
Uniprot Description
DNA-binding transcriptional regulator and coregulator that recognizes and binds to the consensus octamer binding site 5'-AT[A/T]A[T/A]T[A/T]A-3' in promoter of target genes (PubMed:19266028, PubMed:23805044). Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor ISL1 to achieve RGC fate specification in the developing retina. Plays also a role in RGC axon formation and guidance by regulating gene expression of specific target genes. Plays a role in TNFSF11-mediated terminal osteoclast differentiation. Binds chromatin at promoter region of target genes ().
Research Articles on POU4F2
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Product Notes
The POU4F2 pou4f2 (Catalog #AAA1302632) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-265. Full Length of Isoform 2. The amino acid sequence is listed below: MNTIPCTSAA SSSSVPISHP SALAGTHHHH HHHHHHHHQP HQALEGELLE HLSPGLALGA MAGPDGAVVS TPAHAPHMAT MNPMHQAALS MAHAHGLPSH MGCMSDVDAD PRDLEAFAER FKQRRIKLGV TQADVGSALA NLKIPGVGSL SQSTICRFES LTLSHNNMIA LKPILQAWLE EAEKSHREKL TKPELFNGAE KKRKRTSIAA PEKRSLEAYF AIQPRPSSEK IAAIAEKLDL KKNVVRVWFC NQRQKQKRMK YSAGI . It is sometimes possible for the material contained within the vial of "POU domain, class 4, transcription factor 2 (POU4F2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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