Western Blot (WB)
(POU4F2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the POU4F2 antibody detected the POU4F2 protein (arrow).)
Rabbit POU4F2 Polyclonal Antibody | anti-POU4F2 antibody
POU4F2 Antibody (C-term)
Western Blot (WB)
(POU4F2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the POU4F2 antibody detected the POU4F2 protein (arrow).)
Western Blot (WB)
(POU4F2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the POU4F2 antibody detected the POU4F2 protein (arrow).)
transcription factors. POU-domain proteins have been observed to
play important roles in control of cell identity in several
systems. A class IV POU-domain protein, POU4F2 is found in human
retina exclusively within a subpopulation of ganglion cells where
it may play a role in determining or maintaining the identities of
a small subset of visual system neurons.
Budhram-Mahadeo, V.S., et al. Oncogene 27(1):145-154(2008)
Calissano, M., et al. FEBS Lett. 581(13):2490-2496(2007)
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
Samady, L., et al. Int. J. Cancer 118(4):869-878(2006)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]
Uniprot Description
POU4F2: Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 4q31.2
Cellular Component: nuclear speck; nucleus
Molecular Function: chromatin binding
Biological Process: axon guidance; estrogen receptor signaling pathway; transcription, DNA-dependent; axon extension; MAPKKK cascade; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; sensory perception of sound; retina development in camera-type eye; positive regulation of transcription from RNA polymerase II promoter; neuromuscular process controlling balance; positive regulation of cell differentiation; retinal ganglion cell axon guidance
Research Articles on POU4F2
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Product Notes
The POU4F2 pou4f2 (Catalog #AAA9209577) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 311-339. The POU4F2 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's POU4F2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the POU4F2 pou4f2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POU4F2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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