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Septin 2 Positive Control | SEPT2 positive control

Septin 2 Antibody Western Blot Positive Control

Gene Names
SEPT2; DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5
Applications
Western Blot
Synonyms
Septin 2; Septin 2 Antibody Western Blot Positive Control; DIFF6; KIAA0158; NEDD 5; Neural precursor cell expressed developmentally down regulated protein 5; Pnutl3; Protein NEDD5; septin 2 antibody; SEPT2 positive control
Ordering
For Research Use Only!
Form/Format
Western Blot Positive Control
Sequence Length
361
Applicable Applications for SEPT2 positive control
Western Blot (WB)
Application Notes
Western Blot: 1:500
Immunogen
Purified Protein
Expression
Widely expressed. Up-regulated in liver cancer.
Molecular Function
Enzyme regulator activity
Subcellular Location
Cytoplasm, Cytoskeleton, Spindle, Cleavage furrow, Midbody, Cell cortex, Cilium membrane
Preparation and Storage
-20 degree C for long term storage
Related Product Information for SEPT2 positive control
Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating effiecient vesicle transport, and by impeding MAP4 binding to tubulin. Required for progression through mitosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
42,685 Da
NCBI Official Full Name
Septin 2
NCBI Official Synonym Full Names
septin 2
NCBI Official Symbol
SEPT2
NCBI Official Synonym Symbols
DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5
NCBI Protein Information
septin-2
UniProt Protein Name
Septin-2
UniProt Gene Name
SEPT2
UniProt Synonym Gene Names
DIFF6; KIAA0158; NEDD5; NEDD-5
UniProt Entry Name
SEPT2_HUMAN

Uniprot Description

SEPT2: a member of the septin family of proteins. May be involved in the process of cytokinesis. Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell.

Protein type: Hydrolase; Cytoskeletal; Cell development/differentiation; Cell cycle regulation; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: actin cytoskeleton; axoneme; cell cortex; cleavage furrow; cytoplasm; exocyst; midbody; myelin sheath; nonmotile primary cilium; nucleolus; nucleus; perinuclear region of cytoplasm; photoreceptor connecting cilium; spindle; synapse

Molecular Function: enzyme regulator activity; GTP binding; protein binding; protein complex scaffold

Biological Process: cell division; cilium biogenesis; mitosis; neurite development; regulation of catalytic activity; regulation of L-glutamate transport; regulation of protein localization; smoothened signaling pathway

Research Articles on SEPT2

Similar Products

Product Notes

The SEPT2 sept2 (Catalog #AAA543227) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Septin 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500. Researchers should empirically determine the suitability of the SEPT2 sept2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Septin 2, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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