FOLR1 positive control
FOLR1 Positive Control
Gene Names
Folr1; FBP1; Folbp1; Folbp-1
Applications
Western Blot
Synonyms
FOLR1; FOLR1 Positive Control; Western Blot Positive Control Folate receptor Alpha; adult antibody; Adult folate binding protein antibody; FBP antibody; Folate Receptor 1 Adult antibody; Folate receptor 1 antibody; Folate receptor alpha antibody; Folate receptor antibody; FOLR antibody; FOLR1 antibody; FR alpha antibody; KB cells FBP antibody; MOV18 antibody; Ovarian cancer associated antigen antibody; Ovarian tumor associated antigen MOv18 antibody; FOLR1 positive control
Sequence Length
255
Applicable Applications for FOLR1 positive control
Western Blot (WB)
Application Notes
WB: 1:500
Immunogen
Purified protein.
Molecular Function
Receptor
Subcellular Location
Cell Membrane; Cytoplasmic Vesicle; Endosome; Membrane; Secreted
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for FOLR1 positive control
Overview: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.
Structure: Belongs to the folate receptor family.
Expression: Detected in kidney proximal tubules.
Structure: Belongs to the folate receptor family.
Expression: Detected in kidney proximal tubules.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,449 Da
NCBI Official Full Name
folate receptor alpha
NCBI Official Synonym Full Names
folate receptor 1 (adult)
NCBI Official Symbol
Folr1
NCBI Official Synonym Symbols
FBP1; Folbp1; Folbp-1
NCBI Protein Information
folate receptor alpha
UniProt Protein Name
Folate receptor alpha
Protein Family
UniProt Gene Name
Folr1
UniProt Synonym Gene Names
Fbp1; Folbp1; FR-alpha
Uniprot Description
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.
Research Articles on FOLR1
Similar Products
Product Notes
The FOLR1 folr1 (Catalog #AAA5400704) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FOLR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500. Researchers should empirically determine the suitability of the FOLR1 folr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOLR1, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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