FAK1 positive control
FAK1 Positive Control
Gene Names
PTK2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
Applications
Western Blot
Synonyms
FAK1; FAK1 Positive Control; FADK 1; FADK; FAK 1; FAK related non kinase polypeptide; Focal adhesion kinase 1; Focal adhesion Kinase; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; FRNK; p125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein Tyrosine Kinase Cytoplasmic; Protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2 antibody; FAK1 positive control
Form/Format
Western Blot Positive Control
Sequence Length
1074
Applicable Applications for FAK1 positive control
Western Blot (WB)
Application Notes
Western Blot: 1:500
Immunogen
Purified Protein
Expression
Detected in B and T-lymphocytes. Isoform 1 and isoform 6 are detected in lung fibroblasts (at protein level). Ubiquitous.
Molecular Function
Developmental protein; Kinase; Transferase; Tyrosine-protein kinase
Structure
Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.
Contains 1 FERM domain.
Contains 1 protein kinase domain.
Contains 1 FERM domain.
Contains 1 protein kinase domain.
Subcellular Location
Cell junction degree focal adhesion
Cell membrane; Peripheral membrane protein; Cytoplasmic side
Cytoplasm degree cell cortex
Cytoplasm degree cytoskeleton
Cytoplasm degree cytoskeleton degree microtubule organizing center degree centrosome
Nucleus
Cell membrane; Peripheral membrane protein; Cytoplasmic side
Cytoplasm degree cell cortex
Cytoplasm degree cytoskeleton
Cytoplasm degree cytoskeleton degree microtubule organizing center degree centrosome
Nucleus
Preparation and Storage
-20 degree C for long term storage
Related Product Information for FAK1 positive control
Western Blot Positive Control Focal Adhesion Kinase 1
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
114,157 Da
NCBI Official Full Name
focal adhesion kinase 1 isoform b
NCBI Official Synonym Full Names
protein tyrosine kinase 2
NCBI Official Symbol
PTK2
NCBI Official Synonym Symbols
FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
NCBI Protein Information
focal adhesion kinase 1
UniProt Protein Name
PTK2 protein tyrosine kinase 2 isoform b variant
UniProt Entry Name
Q59GM6_HUMAN
NCBI Description
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]
Research Articles on FAK1
Similar Products
Product Notes
The FAK1 (Catalog #AAA542753) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FAK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500. Researchers should empirically determine the suitability of the FAK1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FAK1, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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