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EGR2 positive control

EGR2 Positive Control

Gene Names
Egr2; Egr-2; Zfp-6; Krox20; NGF1-B; Zfp-25; Krox-20
Applications
Western Blot
Synonyms
EGR2; EGR2 Positive Control; Western Blot Positive Control E3 SUMO-protein ligase EGR2/KROX20 Antibody; AT591 antibody; CMT1D antibody; CMT4E antibody; E3 SUMO-protein ligase EGR2 antibody; Early growth response 2 antibody; EGR-2 antibody; FLJ14547 antibody; KROX 20 Drosophila homolog antibody; KROX20 antibody; Zinc finger protein Krox-20 antibody; EGR2 positive control
Ordering
For Research Use Only!
Sequence Length
420
Applicable Applications for EGR2 positive control
Western Blot (WB)
Application Notes
WB: 1:2,500-1:5,000
Immunogen
Purified Protein
Molecular Function
chromatin binding; DNA binding; HMG box domain binding; ligase activity; metal ion binding; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; transcriptional activator activ
Subcellular Location
Nucleus
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for EGR2 positive control
Overview: Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.

Structure: Belongs to the EGR C2H2-type zinc-finger protein family.

Expression: Expressed in mammary tumors (at protein level). Expressed mainly in adult thymus and embryonic nervous system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,500 Da
NCBI Official Full Name
E3 SUMO-protein ligase EGR2 isoform 2
NCBI Official Synonym Full Names
early growth response 2
NCBI Official Symbol
Egr2
NCBI Official Synonym Symbols
Egr-2; Zfp-6; Krox20; NGF1-B; Zfp-25; Krox-20
NCBI Protein Information
E3 SUMO-protein ligase EGR2
UniProt Protein Name
E3 SUMO-protein ligase EGR2
Protein Family
UniProt Gene Name
Egr2
UniProt Synonym Gene Names
Egr-2; Krox-20; Zfp-25; EGR-2

Uniprot Description

Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes.

Research Articles on EGR2

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Product Notes

The EGR2 egr2 (Catalog #AAA5400722) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's EGR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2,500-1:5,000. Researchers should empirically determine the suitability of the EGR2 egr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EGR2, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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