Porcine Interleukin 24 (IL-24) ELISA Kit | IL-24 elisa kit

Porcine Interleukin 24 (IL-24) ELISA Kit

Gene Names

IL24; C49A; FISP; MDA7; MOB5; ST16; IL10B

Reactivity

Porcine

Synonyms

Interleukin 24 (IL-24); Porcine Interleukin 24 (IL-24) ELISA Kit; IL-24 elisa kit

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Cat. Num. AAA2601239 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Porcine

Sequence Length

207

Preparation and Storage

Store all reagents at 2-8 degree C.

NCBI and Uniprot Product Information

NCBI GI #

16307185

NCBI GeneID

11009

Molecular Weight

7,347 Da

NCBI Official Full Name

Interleukin 24

NCBI Official Synonym Full Names

interleukin 24

NCBI Official Symbol

IL24

NCBI Official Synonym Symbols

C49A; FISP; MDA7; MOB5; ST16; IL10B

NCBI Protein Information

interleukin-24; melanocyte-associated Mda-7; IL-4-induced secreted protein; melanoma differentiation-associated gene 7 protein; suppression of tumorigenicity 16 (melanoma differentiation)

UniProt Protein Name

Interleukin-24

UniProt Gene Name

IL24

UniProt Synonym Gene Names

MDA7; ST16; IL-24; MDA-7

UniProt Entry Name

IL24_HUMAN

NCBI Description

This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

IL24: Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation. Belongs to the IL-10 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular space; endoplasmic reticulum

Molecular Function: cytokine activity

Biological Process: negative regulation of cell proliferation; wound healing; apoptosis; positive regulation of cell proliferation; positive regulation of caspase activity; positive regulation of JAK-STAT cascade; immune response; negative regulation of caspase activity; inflammatory response; negative regulation of cell migration; serine phosphorylation of STAT3 protein; positive regulation of tyrosine phosphorylation of Stat3 protein

Research Articles on IL-24

1. elevated gene expression in Mexican mestizo patients with active Crohn's disease

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Product Notes

The Porcine IL-24 il24 (Catalog #AAA2601239) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2601239 ELISA Kit recognizes Porcine IL-24. It is sometimes possible for the material contained within the vial of "Interleukin 24 (IL-24), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Porcine Interleukin 24 (IL-24) ELISA Kit | IL-24 elisa kit