Porcine crystallin, beta A1 (CRYBA1) ELISA Kit | CRYBA1 elisa kit

Porcine crystallin, beta A1 (CRYBA1) ELISA Kit

Cat. Num. AAA7253556

• Gene Names: CRYBA1; CRYB1; CTRCT10
• Reactivity: Porcine
• Synonyms: crystallin; beta A1 (CRYBA1); Porcine crystallin; beta A1 (CRYBA1) ELISA Kit; CRYBA1 elisa kit

• Reactivity: Porcine

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for CRYBA1 elisa kit

Neurobiology

NCBI and Uniprot Product Information

• NCBI GI #: 109730599
• NCBI GeneID: 1411
• Molecular Weight: 23,191 Da
• NCBI Official Full Name: Crystallin, beta A1
• NCBI Official Synonym Full Names: crystallin, beta A1
• NCBI Official Symbol: CRYBA1
• NCBI Official Synonym Symbols: CRYB1; CTRCT10
• NCBI Protein Information: beta-crystallin A3; crystallin, beta A3; eye lens structural protein
• UniProt Protein Name: Beta-crystallin A3
• Protein Family: Beta-crystallin
• UniProt Gene Name: CRYBA1
• UniProt Synonym Gene Names: CRYB1
• UniProt Entry Name: CRBA1_HUMAN

NCBI Description

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]

Uniprot Description

CRYBA1: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital zonular cataract with sutural opacities. Two splice-variant isoforms have been described.

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein homodimerization activity; structural constituent of eye lens

Biological Process: lens development in camera-type eye; visual perception

Disease: Cataract 10, Multiple Types