Western Blot (WB)
(ZNF197 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ZNF197 antibody detected the ZNF197 protein (arrow).)
Rabbit anti-Human ZNF197 Polyclonal Antibody | anti-ZNF197 antibody
ZNF197 Antibody (N-term)
Western Blot (WB)
(ZNF197 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ZNF197 antibody detected the ZNF197 protein (arrow).)
Western Blot (WB)
(ZNF197 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ZNF197 antibody detected the ZNF197 protein (arrow).)
Immunohistochemistry (IHC)
(ZNF197 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZNF197 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ZNF197 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZNF197 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
superfamily, members of which are regulatory proteins characterized
by nucleic acid-binding zinc finger domains. The encoded protein
contains 20 tandemly arrayed C2H2-type zinc fingers, a
Kruppel-associated box (KRAB) domain, and a SCAN box. This
transcript turns over rapidly and contains 3' UTR AUUUA motifs,
which are often a hallmark of rapid turnover. It is overexpressed
in some thyroid papillary carcinomas. ZNF197 is located in a
cluster of zinc finger genes at 3p21. Two alternatively spliced
transcripts encoding different isoforms have been described.
Gonsky, R., et al. Nucleic Acids Res. 25(19):3823-3831(1997)
Calabro, V., et al. Hum. Genet. 95(1):18-21(1995)
Pengue, G., et al. Hum. Mol. Genet. 2(6):791-796(1993)
NCBI and Uniprot Product Information
NCBI Description
This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
ZNF197: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 3p21
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on ZNF197
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Product Notes
The ZNF197 znf197 (Catalog #AAA9214898) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 314-343. The ZNF197 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF197 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the ZNF197 znf197 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF197, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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