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Rabbit anti-Human ZMYND11 Polyclonal Antibody | anti-ZMYND11 antibody

ZMYND11 Antibody, HRP conjugated

Gene Names
ZMYND11; BS69; BRAM1; MRD30
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
ZMYND11; Polyclonal Antibody; ZMYND11 Antibody; HRP conjugated; Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; Bone morphogenetic protein receptor-associated molecule 1; Protein BS69; BRAM1; BS69; anti-ZMYND11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
548
Applicable Applications for anti-ZMYND11 antibody
ELISA (EIA)
Immunogen
Recombinant Human Zinc finger MYND domain-containing protein 11 protein (363-513AA)
Conjugation
HRP
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-ZMYND11 antibody
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66,519 Da
NCBI Official Full Name
zinc finger MYND domain-containing protein 11 isoform c
NCBI Official Synonym Full Names
zinc finger MYND-type containing 11
NCBI Official Symbol
ZMYND11
NCBI Official Synonym Symbols
BS69; BRAM1; MRD30
NCBI Protein Information
zinc finger MYND domain-containing protein 11
UniProt Protein Name
Zinc finger MYND domain-containing protein 11
UniProt Gene Name
ZMYND11
UniProt Synonym Gene Names
BRAM1; BS69

NCBI Description

The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

ZMYND11: Corepressor of transcription (Probable).

Protein type: DNA-binding; Transcription regulation; Tumor suppressor

Chromosomal Location of Human Ortholog: 10p15.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: chromatin binding; histone binding; methylated histone residue binding; protein binding; transcription cofactor activity; transcription corepressor activity; zinc ion binding

Biological Process: cell proliferation; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of JNK cascade; negative regulation of transcription from RNA polymerase II promoter

Disease: Mental Retardation, Autosomal Dominant 30

Research Articles on ZMYND11

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Product Notes

The ZMYND11 zmynd11 (Catalog #AAA7052838) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMYND11 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZMYND11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ZMYND11 zmynd11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZMYND11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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