Rabbit anti-Human ZMIZ2 Polyclonal Antibody | anti-ZMIZ2 antibody
ZMIZ2, CT (PIASz1, Zinc Finger MIZ Domain-containing Protein 2, PIAS-like Protein Zimp7, HRIHFB2007, KIAA1886, ZIMP7)
Gene Names
ZMIZ2; NET27; ZIMP7; hZIMP7; KIAA1886; TRAFIP20; DKFZp761I2123
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
ZMIZ2; Polyclonal Antibody; CT (PIASz1; Zinc Finger MIZ Domain-containing Protein 2; PIAS-like Protein Zimp7; HRIHFB2007; KIAA1886; ZIMP7); Anti -ZMIZ2; anti-ZMIZ2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ZMIZ2.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Applicable Applications for anti-ZMIZ2 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100
Immunogen
Synthetic peptide selected from the C-terminal region of human PIASz1 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-ZMIZ2 antibody
PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway. PIAS proteins have been shown to act as transcriptional co-regulators of multiple signaling pathways in various cellular processes. PIASz increases ligand-dependent transcriptional activity of androgen receptor and other nuclear hormone receptors, possibly through alteration of chromatin structure by SWI/SNF-like BAF complexes
Product Categories/Family for anti-ZMIZ2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
96,537 Da
NCBI Official Full Name
zinc finger MIZ domain-containing protein 2 isoform 2
NCBI Official Synonym Full Names
zinc finger, MIZ-type containing 2
NCBI Official Symbol
ZMIZ2
NCBI Official Synonym Symbols
NET27; ZIMP7; hZIMP7; KIAA1886; TRAFIP20; DKFZp761I2123
NCBI Protein Information
zinc finger MIZ domain-containing protein 2; OTTHUMP00000208713; OTTHUMP00000208714; OTTHUMP00000208715; OTTHUMP00000208716; PIAS-like protein Zimp7
UniProt Protein Name
Zinc finger MIZ domain-containing protein 2
Protein Family
UniProt Gene Name
ZMIZ2
UniProt Synonym Gene Names
KIAA1886; ZIMP7
UniProt Entry Name
ZMIZ2_HUMAN
NCBI Description
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM]
Uniprot Description
ZIMP7: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 7p13
Cellular Component: nucleoplasm; mitochondrion; nuclear replication fork; nucleus
Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding
Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
Research Articles on ZMIZ2
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Product Notes
The ZMIZ2 zmiz2 (Catalog #AAA623538) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMIZ2, CT (PIASz1, Zinc Finger MIZ Domain-containing Protein 2, PIAS-like Protein Zimp7, HRIHFB2007, KIAA1886, ZIMP7) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZMIZ2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the ZMIZ2 zmiz2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZMIZ2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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