Western Blot (WB)
(Western blot analysis of ZIP3 in mouse lung tissue lysate with ZIP3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human, Mouse ZIP3 Polyclonal Antibody | anti-ZIP3 antibody
ZIP3 Antibody
Gene Names
SLC39A3; ZIP3; ZIP-3
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
ZIP3; Polyclonal Antibody; ZIP3 Antibody; Solute carrier family 39 member A3; Slc39A3; anti-ZIP3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
314
Applicable Applications for anti-ZIP3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide near the center of human ZIP3.
Target Name
ZIP3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of ZIP3 in mouse lung tissue lysate with ZIP3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of ZIP3 in mouse lung tissue lysate with ZIP3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of ZIP3 in mouse lung tissue with ZIP3 antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of ZIP3 in mouse lung tissue with ZIP3 antibody at 5 ug/mL.)
Related Product Information for anti-ZIP3 antibody
The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
Product Categories/Family for anti-ZIP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,459 Da
NCBI Official Full Name
zinc transporter ZIP3 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 3
NCBI Official Symbol
SLC39A3
NCBI Official Synonym Symbols
ZIP3; ZIP-3
NCBI Protein Information
zinc transporter ZIP3
UniProt Protein Name
Zinc transporter ZIP3
UniProt Gene Name
SLC39A3
UniProt Synonym Gene Names
ZIP3; ZIP-3
UniProt Entry Name
S39A3_HUMAN
Uniprot Description
SLC39A3: Acts as a zinc-influx transporter (Potential). Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: plasma membrane; integral to membrane
Molecular Function: zinc ion transmembrane transporter activity
Biological Process: transmembrane transport
Research Articles on ZIP3
Similar Products
Product Notes
The ZIP3 slc39a3 (Catalog #AAA9411644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZIP3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZIP3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ZIP3 slc39a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZIP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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