Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Hepg2 cells, Primary antibody: 162238(SLC39A5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Rabbit anti-Human ZIP-5 Polyclonal Antibody | anti-ZIP-5 antibody
ZIP-5 Rabbit pAb
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Hepg2 cells, Primary antibody: 162238(SLC39A5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Western Blot (WB)
(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Hepg2 cells, Primary antibody: 162238(SLC39A5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Uniprot Description
SLC39A5: May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status. Belongs to the ZIP transporter (TC 2.A.5) family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: basolateral plasma membrane; integral to membrane
Molecular Function: metal ion transmembrane transporter activity
Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome; BMP signaling pathway; eye development; zinc ion transport; transmembrane transport
Disease: Myopia 24, Autosomal Dominant
Research Articles on ZIP-5
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Product Notes
The ZIP-5 slc39a5 (Catalog #AAA4754892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZIP-5 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZIP-5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the ZIP-5 slc39a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZIP-5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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